Evidence map›Paper›PMID 20377415›Full record

ReviewJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research2010

Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity.

Shahram Salek-Ardakani, Michael Croft

Abstract readReview
In one paragraph

Review in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Combinatorial immunotherapy induces tumor-infiltrating CD8Journal for immunotherapy of cancer · 2021
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Clinical targeting of the TNF and TNFR superfamilies.Nature reviews. Drug discovery · 2013
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shahram Salek-ArdakaniDivision of Molecular Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA. ssalek@liai.org
Michael Croft

Funding

TRM and airway inflammation and remodelingU19AI070535 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2006 to 2025
$34.2M
Treg stability in viral infection and autoimmunityP01AI089624 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PETERS, BJOERN · 2010 to 2014
$10.1M
The Molecular Basis of OX40 on CD4 T CellsR01AI049453 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2003 to 2012
$3.9M
The Role of 4-IBB in T Cell and APC InteractionsR01AI042944 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 1998 to 2010
$2.9M
Regulation of T Cell Tolerance by OX40R01CA091837 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2002 to 2012
$2.5M
TNFR Members in T Cell Immunity to VacciniaR01AI067341 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2006 to 2010
$2.3M
LIGHT_HVEM_BTLA axis in protective anti_viral immunityR01AI087734 · NIAID · UNIVERSITY OF FLORIDA · PI SALEK-ARDAKANI, SHAHRAM · 2011 to 2015
$1.6M
T Cell Memory to Respiratory Viral InfectionsR21AI077079 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SALEK-ARDAKANI, SHAHRAM · 2007 to 2008
$515k
TNFR Members in T Cell Immunity to VacciniaR56AI067341 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2012 to 2012
$348k
NCI NIH HHS CA91837NCI NIH HHS R01 CA091837NIAID NIH HHS AI070535NIAID NIH HHS AI42944NIAID NIH HHS AI49453NIAID NIH HHS AI67341NIAID NIH HHS AI77079NIAID NIH HHS P01 AI089624NIAID NIH HHS R01 AI042944NIAID NIH HHS R01 AI049453NIAID NIH HHS R01 AI067341NIAID NIH HHS R01 AI087734NIAID NIH HHS R21 AI077079NIAID NIH HHS R56 AI067341NIAID NIH HHS U19 AI070535
6 · The paper itself

Abstract

CD8 memory T cells can play a critical role in protection against repeated exposure to infectious agents such as viruses, yet can also contribute to the immunopathology associated with these pathogens. Understanding the mechanisms that control effective memory responses has important ramifications for vaccine design and in the management of adverse immune reactions. Recent studies have implicated several members of the tumor necrosis factor receptor (TNFR) family as key stimulatory and inhibitory molecules involved in the regulation of CD8 T cells. In this review, we discuss their control of the generation, persistence, and reactivation of CD8 T cells during virus infection.

Indexed as

AnimalsCD8-Positive T-LymphocytesHumansImmunityImmunologic MemoryReceptors, Tumor Necrosis FactorTumor Necrosis FactorsVirus DiseasesReceptors, Tumor Necrosis FactorTumor Necrosis Factors

Identifiers

PMID20377415
PMCPMC3001890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.