Evidence map›Paper›PMID 20376923›Full record

ReviewInternational journal of data mining and bioinformatics2010

Matrix factorisation methods applied in microarray data analysis.

Andrew V Kossenkov, Michael F Ochs

Open access · greenAbstract readReview
In one paragraph

Review in International journal of data mining and bioinformatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Matrix Factorization for Transcriptional Regulatory Network Inference.IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology proceedings. IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology · 2012
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Andrew V KossenkovThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA. akossenkov@wistar.org
Michael F Ochs
Johns Hopkins University · USThe Wistar Institute · US

Funding

An Open-Source Algorithm Isolating Overlapping Signatures in Microarray DataR21LM009382 · NLM · JOHNS HOPKINS UNIVERSITY · PI OCHS, MICHAEL F · 2008 to 2009
$444k
Identifying Genetic Factors for Predisposition in Polygenic DiseasesR03LM008932 · NLM · JOHNS HOPKINS UNIVERSITY · PI OCHS, MICHAEL F · 2006 to 2008
$248k
NLM NIH HHS LM008932NLM NIH HHS LM009382NLM NIH HHS R03 LM008932NLM NIH HHS R21 LM009382
6 · The paper itself

Abstract

Numerous methods have been applied to microarray data to group genes into clusters that show similar expression patterns. These methods assign each gene to a single group, which does not reflect the widely held view among biologists that most, if not all, genes in eukaryotes are involved in multiple biological processes and therefore will be multiply regulated. Here, we review several methods of matrix factorisation that identify patterns of behaviour in transcriptional response and assign genes to multiple patterns. We focus on these methods rather than traditional clustering methods applied to microarray data, which assign one gene to one cluster.

Indexed as

Computational BiologyDatabases, GeneticEukaryotaOligonucleotide Array Sequence AnalysisPattern Recognition, Automated

Identifiers

PMID20376923
PMCPMC2998896
OpenAlexW2130715080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.