ArticlePloS one2010
Association and linkage analysis of aluminum tolerance genes in maize.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 101 citations in OpenAlex.
- From QTL mapping to genome editing: advances and integrated strategies for improving aluminum tolerance in crops.Frontiers in plant science · 2026Review
- Molecular insights into salinity tolerance in Thymus daenensis: Scot and ISSR marker discovery in polycross-derived genotypes.BMC plant biology · 2025Article
- Genetic dissection of seedling root architecture under aluminium toxicity in tropical maize (Frontiers in plant science · 2025Article
- Brown midrib mutant and genome-wide association analysis uncover lignin genes for disease resistance in maize.The plant genome · 2023Article
- Elucidating the patterns of pleiotropy and its biological relevance in maize.PLoS genetics · 2023Article
- Combining GWAS, Genome-Wide Domestication and a Transcriptomic Analysis Reveals the Loci and Natural Alleles of Salt Tolerance in Rice (Frontiers in plant science · 2022Article
- Review
- Temporal genetic patterns of root growth in Brassica napus L. revealed by a low-cost, high-efficiency hydroponic system.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Association Mapping Analysis for Fruit Quality Traits inFrontiers in plant science · 2018Article
- Association Analysis and Identification of ZmHKT1;5 Variation With Salt-Stress Tolerance.Frontiers in plant science · 2018Article
- GWAS analysis in spring barley (Hordeum vulgare L.) for morphological traits exposed to drought.PloS one · 2018Article
- Genome-wide association mapping of aluminum toxicity tolerance and fine mapping of a candidate gene for Nrat1 in rice.PloS one · 2018Article
- Association Mapping of Yield and Yield-related Traits Under Reproductive Stage Drought Stress in Rice (Oryza sativa L.).Rice (New York, N.Y.) · 2017Article
- Analysis of the genetic architecture of maize ear and grain morphological traits by combined linkage and association mapping.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Association Mapping of Ferrous, Zinc, and Aluminum Tolerance at the Seedling Stage inFrontiers in plant science · 2017Article
- A Major Locus for Manganese Tolerance Maps on Chromosome A09 in a Doubled Haploid Population ofFrontiers in plant science · 2017Article
- Combined linkage and association mapping identifies a major QTL (qRtsc8-1), conferring tar spot complex resistance in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Multigenic Control of Pod Shattering Resistance in Chinese Rapeseed Germplasm Revealed by Genome-Wide Association and Linkage Analyses.Frontiers in plant science · 2016Article
- Genomic Regions Associated with Root Traits under Drought Stress in Tropical Maize (Zea mays L.).PloS one · 2016Article
- Genome-wide association study of 29 morphological traits in Aegilops tauschii.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAluminum (Al) toxicity is a major worldwide constraint to crop productivity on acidic soils. Al becomes soluble at low pH, inhibiting root growth and severely reducing yields. Maize is an important staple food and commodity crop in acidic soil regions, especially in South America and Africa where these soils are very common. Al exclusion and intracellular tolerance have been suggested as two important mechanisms for Al tolerance in maize, but little is known about the underlying genetics. METHODOLOGY: An association panel of 282 diverse maize inbred lines and three F2 linkage populations with approximately 200 individuals each were used to study genetic variation in this complex trait. Al tolerance was measured as net root growth in nutrient solution under Al stress, which exhibited a wide range of variation between lines. Comparative and physiological genomics-based approaches were used to select 21 candidate genes for evaluation by association analysis.
conclusionsSix candidate genes had significant results from association analysis, but only four were confirmed by linkage analysis as putatively contributing to Al tolerance: Zea mays AltSB like (ZmASL), Zea mays aluminum-activated malate transporter2 (ALMT2), S-adenosyl-L-homocysteinase (SAHH), and Malic Enzyme (ME). These four candidate genes are high priority subjects for follow-up biochemical and physiological studies on the mechanisms of Al tolerance in maize. Immediately, elite haplotype-specific molecular markers can be developed for these four genes and used for efficient marker-assisted selection of superior alleles in Al tolerance maize breeding programs.
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