ArticlePloS one2010
Characterization of the primo-vascular system in the abdominal cavity of lung cancer mouse model and its differences from the lymphatic system.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Bundle structures inside the deep cervical lymphatic vessels of mice.Scientific reports · 2024Article
- The involvement of the primo vascular system in local enteritis and its modification by electroacupuncture.Frontiers in immunology · 2022Article
- Active interfacial dynamic transport of fluid in a network of fibrous connective tissues throughout the whole body.Cell proliferation · 2020Review
- Various stem cells in acupuncture meridians and points and their putative roles.Journal of traditional and complementary medicine · 2018Review
- Ultrastructure of a Mobile Threadlike Tissue Floating in a Lymph Vessel.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- Hypothesis on the Treatment of Gliomas with Acupuncture at the Primo Node Corresponding toMedical acupuncture · 2015Article
- Fascia and Primo Vascular System.Evidence-based complementary and alternative medicine : eCAM · 2015Review
- Comparison of Alcian Blue, Trypan Blue, and Toluidine Blue for Visualization of the Primo Vascular System Floating in Lymph Ducts.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Primo Vascular System: An Endothelial-to-Mesenchymal Potential Transitional Tissue Involved in Gastric Cancer Metastasis.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Histological similarity of primo vascular systems derived from three internal organs of rats.Integrative medicine research · 2013Article
- Discovery of endothelium and mesenchymal properties of primo vessels in the mesentery.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- 50 years of bong-han theory and 10 years of primo vascular system.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Preliminary Research of Relationship between Acute Peritonitis and Celiac Primo Vessels.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Observation of a long primo vessel in a lymph vessel from the inguinal node of a rabbit.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- The characteristics of action potentials in primo vessels and the effects of acetylcholine injection to the action potentials.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Review and Comment on the Relationship between Primo Vascular System and Meridians.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Primo vascular system accompanying a blood vessel from tumor tissue and a method to distinguish it from the blood or the lymph system.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Differentiating blood, lymph, and primo vessels by residual time characteristic of fluorescent nanoparticles in a tumor model.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Mathematical Distinction in Action Potential between Primo-Vessels and Smooth Muscle.Evidence-based complementary and alternative medicine : eCAM · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer growth and dissemination have been extensively studied for a long time. Nevertheless, many new observations on anatomy and histopathology of cancer events are still reported such as formation of a vasculogenic-like network inside aggressive tumors. In this research, new kinds of micro-conduits, named primo-vessels, were found inside the abdominal cavity of NCI-H460 lung cancer murine xenograft models. These vascular threads were largely distributed on the surfaces of various organs and were often connected to peritoneal tumor nodules. Histological and immunofluorescent investigations showed that the primo-vessels had characteristic features that were distinctively different from those of similar-looking lymphatic vessels. They had multiple channels surrounded with loose collageneous matrices, which is in contrast to the single-channel structure of other vascular systems. The rod-shaped nuclei aligned longitudinally along the channels were assumed to be the endothelial cells of the primo-vessels, but LYVE-1, a specific marker of lymphatics, was not expressed, which indicates a clear difference from lymphatic endothelial cells. Taken together these findings on and characterization of the novel threadlike vascular structures in cancer models may have important implications for cancer prognosis and for therapy.
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