ReviewPlastic and reconstructive surgery2010
A guide to organizing a multicenter clinical trial.
Review in Plastic and reconstructive surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures. The Wrist and Radius Injury Surgical Trial (WRIST)
MUSCLE - Nordic and Free Walking in People With Multiple Sclerosis: Clinical-functional, Motor Control, and Gait Analysis Findings: a Randomized Controlled Multicentre Clinical Trials
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Continuous Fragility Index of Statistically Significant Findings in Randomized Controlled Trials That Compare Interventions for Anterior Shoulder Instability.The American journal of sports medicine · 2024Pooled it
- Effectiveness of virtual-walking intervention combined with exercise on improving pain and function in incomplete spinal cord injury: a feasibility study.Spinal cord series and cases · 2024Trial
- Cost-effectiveness of pirfenidone for patients with cancer and grade 2 or grade 3 radiation-induced lung injury: A modeling study.PLoS medicine · 2026Article
- Insights from the trial innovation network's initial consultation process.Journal of clinical and translational science · 2025Article
- Efficacy and safety of low-molecular-weight collagen peptides in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial.Frontiers in nutrition · 2025Article
- Analyzing collaborations in clinical trials in Korea using association rule mining.Translational and clinical pharmacology · 2024Article
- Global collaborative research in metabolic and bariatric surgery (GCRMBS): current status and directions for the future.BMC surgery · 2024Review
- The current status and global trends of clinical trials related to robotic surgery: a bibliometric and visualized study.Journal of robotic surgery · 2024Article
- Fluid biomarkers in cerebral amyloid angiopathy.Frontiers in neuroscience · 2024Review
- Application of Statistical Methods for Central Statistical Monitoring and Implementations on the German Multiple Sclerosis Registry.Therapeutic innovation & regulatory science · 2023Article
- A consensus score to combine inferences from multiple centres.Mammalian genome : official journal of the International Mammalian Genome Society · 2023Article
- Relationship between health literacy and physical function of patients participating in phase I cardiac rehabilitation: a multicenter clinical study.Heart and vessels · 2023Article
- Multi-centric clinic trials in evidence-based research - A narrative review on the Indian scenario.Journal of family medicine and primary care · 2023Review
- Predictive factors for walking in acute stroke patients: a multicenter study using classification and regression tree analysis.Journal of physical therapy science · 2023Article
- Protocol of the CONSORT and SPIRIT Extension for multicenter clinical trials.Frontiers in public health · 2023Article
- The Milestones of Clinical Research for Young Generalist Physicians: Conducting and Publishing Studies.International journal of general medicine · 2023Article
- Health Literacy Is Associated with Activities of Daily Living of Patients Participating in Cardiac Rehabilitation: A Multicenter Clinical Study.International journal of environmental research and public health · 2022Article
- Prediction modelling in the early detection of neonatal sepsis.World journal of pediatrics : WJP · 2022Review
- Clinical Characteristics and Current Managements for Patients with Chronic Subdural Hematoma : A Retrospective Multicenter Pilot Study in the Republic of Korea.Journal of Korean Neurosurgical Society · 2022Article
- Osseodensification effect on implants primary and secondary stability: Multicenter controlled clinical trial.Clinical implant dentistry and related research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Multicenter clinical trials are important research tools. Planning a multicenter clinical trial is a long and arduous task that requires substantial preparation time. In this guide, the authors discuss the steps used to plan a multicenter clinical trial. A preplanning phase, which involves formulating and refining a research question and conducting pilot studies, is detailed, and the planning phase, which involves the acquisition of funding to support the coordination and preparation of a multicenter clinical trial, culminating in the submission of an R01 grant, is described. An essential asset to planning a multicenter clinical trial is the fluidity with which all collaborators work together toward a common vision. The philosophy among collaborators should be consensus and commitment and is emphasized by the development of a consensus assisted study protocol. Most important are the recruitment of centers and co-investigators who are dedicated, collaborative, and selfless in the team effort to achieve goals that cannot be reached by a single-center effort.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.