ReviewAging2010
Clock genes, hair growth and aging.
Review in Aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 63 citations in OpenAlex.
- Hair Follicles as Micro-Organs: MicroRNA-Mediated Control of Growth, Cycling, and Fiber Traits.Biomolecules · 2026Review
- Anti-skin aging effects of black ginseng extracts through regulating inflammatory factors and the CLOCK-ERK pathway in mice.Journal of ginseng research · 2026Article
- Designing and Evaluating Circadian Experiments on Mouse Skin.The Journal of investigative dermatology · 2025Review
- The rhythms of histones in regeneration: The epigenetic modifications determined by clock genes.Experimental dermatology · 2024Article
- How and Why the Circadian Clock Regulates Proliferation of Adult Epithelial Stem Cells.Stem cells (Dayton, Ohio) · 2023Article
- Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss.Journal of clinical medicine · 2023Review
- Signaling pathways in hair aging.Frontiers in cell and developmental biology · 2023Review
- In Vitro Biological Activity and In Vivo Human Study of Porcine-Placenta-Extract-Loaded Nanovesicle Formulations for Skin and Hair Rejuvenation.Pharmaceutics · 2022Article
- Elucidation of the Potential Hair Growth-Promoting Effect ofBiomedicines · 2022Article
- β-Catenin Signaling Evokes Hair Follicle Senescence by Accelerating the Differentiation of Hair Follicle Mesenchymal Progenitors.Frontiers in cell and developmental biology · 2022Article
- Critical Roles of the Circadian Transcription FactorFrontiers in endocrinology · 2022Review
- The circadian clock and diseases of the skin.FEBS letters · 2021Review
- Transcriptome profiling reveals transcriptional and alternative splicing regulation in the early embryonic development of hair follicles in the cashmere goat.Scientific reports · 2019Article
- The molecular clock in the skin, its functionality, and how it is disrupted in cutaneous melanoma: a new pharmacological target?Cellular and molecular life sciences : CMLS · 2019Review
- Article
- Biological Rhythms in the Skin.International journal of molecular sciences · 2016Review
- The short-lived African turquoise killifish: an emerging experimental model for ageing.Disease models & mechanisms · 2016Review
- Aging hair follicles rejuvenated by transplantation to a young subcutaneous environment.Cell cycle (Georgetown, Tex.) · 2016Article
- Resting no more: re-defining telogen, the maintenance stage of the hair growth cycle.Biological reviews of the Cambridge Philosophical Society · 2015Review
- The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity.Journal of biological rhythms · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Hair follicles undergo continuous cycles of growth, involution and rest. This process, referred to as the hair growth cycle, has a periodicity of weeks to months. At the same time, skin and hair follicles harbor a functional circadian clock that regulates gene expression with a periodicity of approximately twenty four hours. In our recent study we found that circadian clock genes play a role in regulation of the hair growth cycle during synchronized hair follicle cycling, uncovering an unexpected connection between these two timing systems within skin. This work, therefore, indicates a role for circadian clock genes in a cyclical process of much longer periodicity than twenty four hours.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.