ReviewClinical microbiology reviews2010
Clinical and laboratory update on blastomycosis.
Review in Clinical microbiology reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
154 citing papers in PubMed, 2 syntheses or guidelines pooled it, 440 citations in OpenAlex.
- Endemic Systemic Mycoses in Italy: A Systematic Review of Literature and a Practical Update.Mycopathologia · 2023Pooled it
- The microbiome of bat guano: for what is this knowledge important?Applied microbiology and biotechnology · 2021Pooled it
- Disseminated Blastomycosis With Pulmonary, Cutaneous, and Splenic Involvement in a Construction Worker: A Case Report.Clinical case reports · 2026Article
- First Report of Fatal Disseminated Blastomyces percursus Infection in a Liver Transplant Recipient in Iran, a Non-endemic Country: A Case Report.Mycopathologia · 2026Article
- Article
- Hybrid histidine kinases and antifungal warfare in thermal dimorphic fungi.Antimicrobial agents and chemotherapy · 2026Review
- Article
- Role of Blastomyces BAD-1 IgG Enzyme Immunoassay (EIA) for the diagnosis of blastomycosis in persons residing in an endemic area.Medical mycology · 2026Article
- Cavitary Pulmonary Blastomycosis and an Incidental Retroperitoneal Ganglioneuroma Mimicking Metastatic Disease.Cureus · 2026Article
- Cutaneous clues to a fungal culprit: disseminated Blastomycosis presenting as inflammatory monoarthritis - a Case Report.Frontiers in medicine · 2026Article
- Necrotizing pneumonia due to blastomycosis: Diagnostic challenges and the emerging role of cell-free DNA testing.IDCases · 2026Article
- Disseminated blastomycosis in pregnancy presenting with arthritis and cutaneous lesions.IDCases · 2026Article
- Three cases of cutaneous blastomycosis in immunocompetent patients.JAAD case reports · 2025Article
- Blastomycosis Masquerading as Tuberculosis: A Diagnostic Challenge in a Patient With Diabetes.Cureus · 2025Article
- Diagnosing Blastomycosis: A Review of Laboratory Methods and Clinical Utility.Journal of fungi (Basel, Switzerland) · 2025Review
- Practical Guidance for Clinical Microbiology Laboratories: Antibody and antigen detection methods for dimorphic fungal infections.Clinical microbiology reviews · 2025Review
- Article
- Central nervous system blastomycosis in an immunocompetent child.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Article
- A rare case of miliary blastomycosis.Respiratory medicine case reports · 2025Article
- Acquired Blastomycosis infection in a patient with prior Roux-en-Y bariatric surgery: A case report.IDCases · 2025Article
94 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blastomycosis is endemic in regions of North America that border the Great Lakes and the St. Lawrence River, as well as in the Mississippi River and Ohio River basins. Men are affected more often than women and children because men are more likely to participate in activities that put them at risk for exposure to Blastomyces dermatitidis. Human infection occurs when soil containing microfoci of mycelia is disturbed and airborne conidia are inhaled. If natural defenses in the alveoli fail to contain the infection, lymphohematogenous dissemination ensues. Normal host responses generate a characteristic pyogranulomatous reaction. The most common sites of clinical disease are the lung and skin; osseous, genitourinary, and central nervous system manifestations follow in decreasing order of frequency. Blastomycosis is one of the great mimickers in medicine; verrucous cutaneous blastomycosis resembles malignancy, and mass-like lung opacities due to B. dermatitidis often are confused with cancer. Blastomycosis may be clinically indistinguishable from tuberculosis. Diagnosis is based on culture and direct visualization of round, multinucleated yeast forms that produce daughter cells from a single broad-based bud. Although a long course of amphotericin B is usually curative, itraconazole is also highly effective and is the mainstay of therapy for most patients with blastomycosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.