ReviewClinical microbiology reviews2010
Cardiac involvement with parasitic infections.
Review in Clinical microbiology reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 167 citations in OpenAlex.
- A Systematic Review of the Spectrum of Cardiac Arrhythmias in Sub-Saharan Africa.Global heart · 2020Pooled it
- Myocarditis associated with COVID-19 and its vaccines - a systematic review.Progress in cardiovascular diseasesPooled it
- Myopericarditis Secondary to Toxoplasma Gondii Infection in an Immunocompetent Young Male-A Case Report.Reports (MDPI) · 2026Article
- CD73 activity controls cytotoxic CD4 T-cell response driving myocardial pathology in chronic Chagas disease.Frontiers in immunology · 2026Article
- Gene expression profiling in cardiac tissue of mice chronically infected with Toxoplasma gondii: implications for immune response pathways.European journal of medical research · 2025Article
- Purinergic signaling modulates CD4+ T cells with cytotoxic potential during Trypanosoma cruzi infection.The Journal of clinical investigation · 2025Article
- The Intersection of Heart Failure and Iron Deficiency Anemia: Diagnostic and Therapeutic Approaches.Current cardiology reviews · 2025Review
- A comparative review of myocarditis in pediatrics versus adults: pathogenesis, diagnosis, and management.Frontiers in immunology · 2025Review
- Toxoplasma Gondii infection and cardiovascular mortality: sex-specific differences in a United States population-based cohort study.BMC infectious diseases · 2024Article
- Molecular similarities between the genes for Trypanosoma cruzi microtubule-associated proteins, mammalian interferons, and TRIMs.Parasitology research · 2024Article
- A Strongly Suspected Case of Concomitant Myocarditis in Naegleria fowleri Induced Primary Amoebic Meningoencephalitis.Acta Cardiologica Sinica · 2024Article
- Article
- Infectious factors in myocarditis: a comprehensive review of common and rare pathogens.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Review
- High Prevalence of Bovine Cardiac Cysticercosis in Upper Egypt: An Epidemiological and Histopathological Study.Animals : an open access journal from MDPI · 2024Article
- Beyond the acute phase: a comprehensive literature review of long-term sequelae resulting from infectious diseases.Frontiers in cellular and infection microbiology · 2024Review
- Persistent Biofluid Small-Molecule Alterations Induced byACS infectious diseases · 2023Article
- Myocarditis in connective tissue diseases: an often-overlooked clinical manifestation.Rheumatology international · 2023Review
- Synchronous Left Ventricular and Endocranial Mass.Journal of medical cases · 2023Article
- Review
- Persistent biofluid small molecule alterations induced bybioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parasitic infections previously seen only in developing tropical settings can be currently diagnosed worldwide due to travel and population migration. Some parasites may directly or indirectly affect various anatomical structures of the heart, with infections manifested as myocarditis, pericarditis, pancarditis, or pulmonary hypertension. Thus, it has become quite relevant for clinicians in developed settings to consider parasitic infections in the differential diagnosis of myocardial and pericardial disease anywhere around the globe. Chagas' disease is by far the most important parasitic infection of the heart and one that it is currently considered a global parasitic infection due to the growing migration of populations from areas where these infections are highly endemic to settings where they are not endemic. Current advances in the treatment of African trypanosomiasis offer hope to prevent not only the neurological complications but also the frequently identified cardiac manifestations of this life-threatening parasitic infection. The lack of effective vaccines, optimal chemoprophylaxis, or evidence-based pharmacological therapies to control many of the parasitic diseases of the heart, in particular Chagas' disease, makes this disease one of the most important public health challenges of our time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.