ReviewClinical microbiology reviews2010
Candida infections of the genitourinary tract.
Review in Clinical microbiology reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03115073 (A Phase IIa Randomized, Active-controlled, Double-blind, Dose-escalation Study in Patients With Vulvovaginal Candidiasis to Evaluate Dose Response Relationship of Clinical Efficacy, Safety and Tolerability of Topically Administered ProF-001), which is not on this map. Cited by 285 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase IIa Randomized, Active-controlled, Double-blind, Dose-escalation Study in Patients With Vulvovaginal Candidiasis to Evaluate Dose Response Relationship of Clinical Efficacy, Safety and Tolerability of Topically Administered ProF-001
Who cites it
285 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Candida albicans-A systematic review to inform the World Health Organization Fungal Priority Pathogens List.Medical mycology · 2024Pooled it
- Efficacy of a vaginal tablet as a Persian medicine product on vulvovaginal candidiasis: a double-blind, randomised, placebo-controlled trial.Pharmaceutical biology · 2020Trial
- Honghe Fujie lotion ameliorates pregnancy-associated vulvovaginal candidiasis in mice by inhibiting the activation of NLRP3 inflammasome.Experimental animals · 2026Article
- The Gut-Vagina Axis.Microorganisms · 2026Review
- Escalating Antifungal Resistance AmongPathogens (Basel, Switzerland) · 2026Article
- Distribution and antimicrobial resistance of uropathogens: a 6-year retrospective single-center study (2019-2024).BMC infectious diseases · 2026Article
- Anatomopathological uterine findings ofJournal of medical microbiology · 2026Article
- Candida urinary tract infections, antifungal susceptibility and factors associated with candiduria among pregnant women seeking antenatal care at Murang'a County Referral Hospital, Kenya.BMC pregnancy and childbirth · 2026Article
- Antifungal susceptibility, FKS1 gene expression, and virulence determinants of Candida albicans in pediatric and neonatal candidiasis.BMC infectious diseases · 2026Article
- Biphasic Regulation of Epithelial Antimicrobial Peptides DuringJournal of fungi (Basel, Switzerland) · 2026Article
- Elevated vaginal heparan sulfate correlates with impaired neutrophil killing ofInfection and immunity · 2026Article
- The Role of the Vaginal Microbiome in Gynecological Diseases: Mechanistic Insights and Emerging Interventions.Biology · 2026Review
- Article
- Characteristics and Clinical Relevance of Candiduria in Hospitalized Patients.Journal of clinical medicine · 2026Article
- Interactions betweenInfection and immunity · 2026Article
- Fluconazole-Resistant and Virulence-Associated Yeasts from the Vulva: Evidence of a Potential Reservoir.Journal of fungi (Basel, Switzerland) · 2026Article
- Vulvovaginal candidiasis in rural pregnant populations from Uttar Pradesh, India: species shift, biofilm formation, and resistance trends.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Response ofmSphere · 2026Article
- Unraveling the Nutritional Perspectives of Probiotics and Prebiotics in Female Healthcare.Recent advances in food, nutrition & agriculture · 2026Review
- Article
225 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
All humans are colonized with Candida species, mostly Candida albicans, yet some develop diseases due to Candida, among which genitourinary manifestations are extremely common. The forms of genitourinary candidiasis are distinct from each other and affect different populations. While vulvovaginal candidiasis affects mostly healthy women, candiduria occurs typically in elderly, hospitalized, or immunocompromised patients and in neonates. Despite its high incidence and clinical relevance, genitourinary candidiasis is understudied, and therefore, important questions about pathogenesis and treatment guidelines remain to be resolved. In this review, we summarize the current knowledge about genitourinary candidiasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.