ArticleMolecular biology of the cell2010
Meiotic cohesin promotes pairing of nonhomologous centromeres in early meiotic prophase.
Article in Molecular biology of the cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 33 citations in OpenAlex.
- Heterochromatin in plant meiosis.Nucleus (Austin, Tex.) · 2024Review
- Meiosis in budding yeast.Genetics · 2023Article
- The courtship choreography of homologous chromosomes: timing and mechanisms of DSB-independent pairing.Frontiers in cell and developmental biology · 2023Review
- Chromosome-nuclear envelope tethering - a process that orchestrates homologue pairing during plant meiosis?Journal of cell science · 2020Review
- A ZIP1 separation-of-function allele reveals that centromere pairing drives meiotic segregation of achiasmate chromosomes in budding yeast.PLoS genetics · 2018Review
- Meiotic Centromere Coupling and Pairing Function by Two Separate Mechanisms in Saccharomyces cerevisiae.Genetics · 2017Article
- Article
- A few of our favorite things: Pairing, the bouquet, crossover interference and evolution of meiosis.Seminars in cell & developmental biology · 2016Review
- Article
- Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae.Molecular biology of the cell · 2015Article
- Article
- Couples, pairs, and clusters: mechanisms and implications of centromere associations in meiosis.Chromosoma · 2014Review
- The Chromosomal Courtship Dance-homolog pairing in early meiosis.Current opinion in cell biology · 2014Review
- Global linkage map connects meiotic centromere function to chromosome size in budding yeast.G3 (Bethesda, Md.) · 2013Article
- The cohesion protein SOLO associates with SMC1 and is required for synapsis, recombination, homolog bias and cohesion and pairing of centromeres in Drosophila Meiosis.PLoS genetics · 2013Article
- Multiple opposing constraints govern chromosome interactions during meiosis.PLoS genetics · 2013Article
- Meiotic development in Caenorhabditis elegans.Advances in experimental medicine and biology · 2013Review
- Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes.PLoS genetics · 2012Article
- Positioning of chromosomes in human spermatozoa is determined by ordered centromere arrangement.PloS one · 2012Article
- Differing requirements for RAD51 and DMC1 in meiotic pairing of centromeres and chromosome arms in Arabidopsis thaliana.PLoS genetics · 2012Article
Corrections and comments
- Erratum issuedCorrection.2015 · Bardhan, Amit [Deleted]
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A period of pairing between nonhomologous centromeres occurs early in meiosis in a diverse collection of organisms. This early, homology-independent, centromere pairing, referred to as centromere coupling in budding yeast, gives way to an alignment of homologous centromeres as homologues synapse later in meiotic prophase. The regulation of centromere coupling and its underlying mechanism have not been elucidated. In budding yeast, the protein Zip1p is a major component of the central element of the synaptonemal complex in pachytene of meiosis, and earlier, is essential for centromere coupling. The experiments reported here demonstrate that centromere coupling is mechanistically distinct from synaptonemal complex assembly. Zip2p, Zip3p, and Red1p are all required for the assembly of Zip1 into the synaptonemal complex but are dispensable for centromere coupling. However, the meiotic cohesin Rec8p is required for centromere coupling. Loading of meiotic cohesins to centromeres and cohesin-associated regions is required for the association of Zip1 with these sites, and the association of Zip1 with the centromeres then promotes coupling. These findings reveal a mechanism that promotes associations between centromeres before the assembly of the synaptonemal complex, and they demonstrate that chromosomes are preloaded with Zip1p in a manner that may promote synapsis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.