Evidence map›Paper›PMID 20374659›Full record

SynthesisBMC cancer2010

Moxibustion for cancer care: a systematic review and meta-analysis.

Myeong Soo Lee, Tae-Young Choi, Ji-Eun Park, Song-Shil Lee, Edzard Ernst

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 6 pooled it
24.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02261571 naunknown statusnot on this mapstarted 2014, after this paper: background citation

A Pilot Study to Estimate the Efficacy of Moxibustion Stimulation at Abdominal Acupoints on Quality of Life in Cancer Patients Under Chemotherapy

TypeinterventionalSponsorThe Comprehensive and Integrative Medicine Institute of South KoreaRan2014 to 2015Enrolled20ConditionsCancerArmsMoxibustion
NCT02271607 nacompletednot on this mapstarted 2014, after this paper: background citation

A Pilot Study About The Effects of Indirect-Moxibustion on Bladder- Functional Improvement and Symptoms Management in Patients With Overactive Bladder: A Randomized Controlled Trial

TypeinterventionalSponsorKorean Medicine Hospital of Pusan National UniversityRan2014 to 2015Enrolled24ConditionsOveractive Bladder, Hyperthermia, Urinary Frequency or Urgency Adverse Event, Lower Urinary Tract SymptomsArmsmoxibustion
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 6 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Moxibustion for the treatment of chemotherapy-induced leukopenia: a systematic review of randomized clinical trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. From traditional warming and tonifying to psychoneuroimmunology: theoretical reconstruction and clinical application of moxibustion for cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  11. Article
  12. Complementary and Alternative Therapies in Oncology.International journal of environmental research and public health · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Moxibustion for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review and Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
  18. Changes in skin surface temperature at an acupuncture point with moxibustion.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2013
    Article
  19. How does moxibustion possibly work?Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Myeong Soo LeeDivision of Standard Research, Korea Institute of Oriental Medicine, Daejeon, South Korea. drmslee@gmail.com
Tae-Young Choi
Ji-Eun Park
Song-Shil Lee
Edzard Ernst
Korea Institute of Oriental Medicine · KRPeninsula College of Medicine and Dentistry · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMoxibustion is a traditional Chinese method that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points. Considering moxibustion is closely related to acupuncture, it seems pertinent to evaluate the effectiveness of moxibustion as a treatment of symptoms of cancer. The objective of this review was to systematically assess the effectiveness of moxibustion for supportive cancer care.

methodsWe searched the literature using 11 databases from their inceptions to February 2010, without language restrictions. We included randomised clinical trials (RCTs) in which moxibustion was employed as an adjuvant treatment for conventional medicine in patients with any type of cancer. The selection of studies, data extraction, and validations were performed independently by two reviewers.

resultsFive RCTs compared the effects of moxibustion with conventional therapy. Four RCTs failed to show favourable effects of moxibustion for response rate compared with chemotherapy (n = 229, RR, 1.04, 95% CI 0.94 to 1.15, P = 0.43). Two RCTs assessed the occurrence of side effects of chemotherapy and showed favourable effects of moxibustion. A meta-analysis showed significant less frequency of nausea and vomiting from chemotherapy for moxibustion group (n = 80, RR, 0.38, 95% CIs 0.22 to 0.65, P = 0.0005, heterogeneity: chi2 = 0.18, P = 0.67, I2 = 0%).

conclusionThe evidence is limited to suggest moxibustion is an effective supportive cancer care in nausea and vomiting. However, all studies have a high risk of bias so effectively there is not enough evidence to draw any conclusion. Further research is required to investigate whether there are specific benefits of moxibustion for supportive cancer care.

Indexed as

MoxibustionAntineoplastic AgentsCombined Modality TherapyEvidence-Based MedicineHumansNauseaNeoplasmsQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeVomitingAntineoplastic Agents

Identifiers

PMID20374659
PMCPMC2873382
OpenAlexW1990582861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.