SynthesisTropical medicine & international health : TM & IH2010
Epidemiology and control of trachoma: systematic review.
Synthesis in Tropical medicine & international health : TM & IH, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 7 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- Predictors of trachoma among children aged 1-9 years in Ethiopia: a comprehensive systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Prevalence and associated factors of active trachoma among children of 1 to 9 years in low-income countries of Africa: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Community-level trachoma ecological associations and the use of geospatial analysis methods: A systematic review.PLoS neglected tropical diseases · 2022Pooled it
- The impact of access to water supply and sanitation on the prevalence of active trachoma in Ethiopia: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2021Pooled it
- Relation of Chlamydia trachomatis infections to ectopic pregnancy: A meta-analysis and systematic review.Medicine · 2020Pooled it
- Factors shaping the implementation of the SAFE strategy for trachoma using the Consolidated Framework for Implementation Research: a systematic review.Global health action · 2019Pooled it
- Effect of water, sanitation, and hygiene on the prevention of trachoma: a systematic review and meta-analysis.PLoS medicine · 2014Pooled it
- Mass azithromycin distribution for hyperendemic trachoma following a cluster-randomized trial: A continuation study of randomly reassigned subclusters (TANA II).PLoS medicine · 2018Trial
- Chloroquine-azithromycin combination antimalarial treatment decreases risk of respiratory- and gastrointestinal-tract infections in Malawian children.The Journal of infectious diseases · 2014Trial
- A randomized trial of two coverage targets for mass treatment with azithromycin for trachoma.PLoS neglected tropical diseases · 2013Trial
- Human female genital tract infection by the obligate intracellular bacterium Chlamydia trachomatis elicits robust Type 2 immunity.PloS one · 2013Trial
- Application of smartphone cameras for detecting clinically active trachoma.The British journal of ophthalmology · 2012Trial
- Ocular community state types reveal distinct microbial compositions among microbiomes with implications for trachoma control.bioRxiv : the preprint server for biology · 2026Article
- Chlamydial membrane vesicles deliver the beta barrel outer membrane protein OmpA to mitochondria to inhibit apoptosis.PLoS pathogens · 2026Article
- Impact of evidence-based programmatic adaptations in addressing the persistence and recrudescence of trachoma in Kajiado County, Kenya.International health · 2025Article
- Prevalence of Chlamydia trachomatis in eye specimens of patients suspected of having viral keratitis: a cross-sectional study.New microbes and new infections · 2025Article
- Assessing the effectiveness of the community participation approaches to improve access to mass drug administration for trachoma elimination in a pastoral conflict area of Baringo County, Kenya.PLoS neglected tropical diseases · 2025Article
- Evolutionary dynamics in the genome of ocularMicrobial genomics · 2025Article
- Understanding the impact of covariates for trachoma prevalence prediction using geostatistical methods.BMC global and public health · 2025Article
- Analysis and forecast of the disease burden of trachoma in China and the Global Population over 15 years of age, 1990-2021.PLoS neglected tropical diseases · 2025Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trachoma is the commonest infectious cause of blindness. Recurrent episodes of infection with serovars A-C of Chlamydia trachomatis cause conjunctival inflammation in children who go on to develop scarring and blindness as adults. It was estimated that in 2002 at least 1.3 million people were blind from trachoma, and currently 40 million people are thought to have active disease and 8.2 million to have trichiasis. The disease is largely found in poor, rural communities in developing countries, particularly in sub-Saharan Africa. The WHO promotes trachoma control through a multifaceted approach involving surgery, mass antibiotic distribution, encouraging facial cleanliness and environmental improvements. This has been associated with significant reductions in the prevalence of active disease over the past 20 years, but there remain a large number of people with trichiasis who are at risk of blindness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.