ArticleThe Plant journal : for cell and molecular biology2010
Metabolic profiling reveals local and systemic responses of host plants to nematode parasitism.
Article in The Plant journal : for cell and molecular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed, 186 citations in OpenAlex.
- Integrated omics reveal phenylpropanoid biosynthesis as a key defense pathway against Meloidogyne incognita in Cucumis metuliferus.BMC plant biology · 2026Article
- Dual and Single-species Nematode Infections Distinctly Modulate Defense Metabolism in Brassica nigra Roots.Journal of chemical ecology · 2025Article
- Root-knot nematode infection enhances the performance of a specialist root herbivore via plant-mediated interactions.Plant physiology · 2025Article
- A trehalase-derived MAMP triggers LecRK-V-mediated immune responses inScience advances · 2025Article
- Diurnal rhythms in durum wheat triggered by Rhopalosiphum padi (bird cherry-oat aphid).BMC plant biology · 2025Article
- Dual nematode infection in Brassica nigra affects shoot metabolome and aphid survival in distinct contrast to single-species infection.Journal of experimental botany · 2024Article
- Genetic dissection of Meloidogyne incognita resistance genes based on VIGS functional analysis in Cucumis metuliferus.BMC plant biology · 2024Article
- Syncytium Induced by Plant-Parasitic Nematodes.Results and problems in cell differentiation · 2024Review
- Unraveling the diversity and functions of sugar transporters for sustainable management of wheat rust.Functional & integrative genomics · 2023Review
- Biotechnological Tools to Elucidate the Mechanism of Plant and Nematode Interactions.Plants (Basel, Switzerland) · 2023Review
- Metabolomics and Transcriptomics Reveal the Response Mechanisms ofMicroorganisms · 2023Article
- Article
- Glutathione contributes to plant defence against parasitic cyst nematodes.Molecular plant pathology · 2022Article
- Pattern-triggered immunity against root-knot nematode infection: A minireview.Physiologia plantarum · 2022Article
- From Raffinose Family Oligosaccharides to Sucrose and Hexoses: Gene Expression Profiles Underlying Host-to-Nematode Carbon Delivery inFrontiers in plant science · 2022Article
- Physiological and metabolic analyses provide insight into soybean seed resistance toFrontiers in plant science · 2022Article
- RNA Isolation from Nematode-Induced Feeding Sites in Arabidopsis Roots Using Laser Capture Microdissection.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Leaf herbivory counteracts nematode-triggered repression of jasmonate-related defenses in tomato roots.Plant physiology · 2021Article
- Metabolic Analysis of the Development of the Plant-Parasitic Cyst NematodesInternational journal of molecular sciences · 2021Article
- Advances in the Study of Metabolomics and Metabolites in Some Species Interactions.Molecules (Basel, Switzerland) · 2021Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
The plant parasitic beet cyst nematode Heterodera schachtii induces syncytial feeding structures in Arabidopsis roots. The feeding structures form strong sink tissues that have been suggested to be metabolically highly active. In the present study, metabolic profiling and gene targeted expression analyses were performed in order to study the local and systemic effects of nematode infection on the plant host. The results showed increased levels of many amino acids and phosphorylated metabolites in syncytia, as well as high accumulation of specific sugars such as 1-kestose that do not accumulate naturally in Arabidopsis roots. A correlation-based network analysis revealed highly activated and coordinated metabolism in syncytia compared to non-infected control roots. An integrated analysis of the central primary metabolism showed a clear coherence of metabolite and transcript levels, indicating transcriptional regulation of specific pathways. Furthermore, systemic effects of nematode infection were demonstrated by correlation-based network analysis as well as independent component analysis. 1-kestose, raffinose, alpha,alpha-trehalose and three non-identified analytes showed clear systemic accumulation, indicating future potential for diagnostic and detailed metabolic analyses. Our studies open the door towards understanding the complex remodelling of plant metabolism in favour of the parasitizing nematode.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.