Evidence map›Paper›PMID 20373736›Full record

ArticleJournal of the American Chemical Society2010

Membrane lipids influence protein complex assembly-disassembly.

Leah Shin, Won Jin Cho, Jeremy D Cook, Timothy L Stemmler, Bhanu P Jena

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. The neuronal porosome complex in health and disease.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
  4. Article
  5. Review
  6. Article
  7. NeuronalJournal of molecular structure · 2014
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Membrane-directed molecular assembly of the neuronal SNARE complex.Journal of cellular and molecular medicine · 2011
    Article
  14. Article
  15. Porosome in Cystic Fibrosis.Discoveries (Craiova, Romania)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leah ShinDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.
Won Jin Cho
Jeremy D Cook
Timothy L Stemmler
Bhanu P Jena
Wayne State University · US

Funding

Structural Insights into the Function of FrataxinR01DK068139 · NIDDK · WAYNE STATE UNIVERSITY · PI STEMMLER, TIMOTHY LOUIS · 2005 to 2015
$3.5M
UNDERSTANDING MEMBRANE FUSION A BIOENGINEERING APPROACHR01EB000303 · NIBIB · WAYNE STATE UNIVERSITY · PI JENA, BHANU P · 2002 to 2004
$1.2M
NIBIB NIH HHS R01 EB000303NIDDK NIH HHS R01 DK068139
6 · The paper itself

Abstract

Approximately 11% smaller t-/v-SNARE ring complexes are generated using 50 nm cholesterol-associated vesicles as opposed to vesicles containing L-alpha-lysophosphatidylcholine (LPC), as observed using atomic force microscopy. Circular dichroism spectroscopy demonstrated that in the presence of LPC as opposed to cholesterol, N-ethylmaleimide-sensitive factor + adenosine triphosphate induces disassembly of beta-sheet structures but not the alpha-helical contents within the t-/v-SNARE complex.

Indexed as

CholesterolCircular DichroismLysophosphatidylcholinesMembrane LipidsMicroscopy, Atomic ForceProtein BindingProtein Structure, SecondarySNARE ProteinsCholesterolLysophosphatidylcholinesMembrane LipidsSNARE Proteins

Identifiers

PMID20373736
PMCPMC2862647
OpenAlexW2040740793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.