ReviewDialogues in clinical neuroscience2010
Nature and nurture in neuropsychiatric genetics: where do we stand?
Review in Dialogues in clinical neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Article
- The Difficult Path to the Discovery of Novel Treatments in Psychiatric Disorders.Advances in neurobiology · 2023Article
- The Roles of Par3, Par6, and aPKC Polarity Proteins in Normal Neurodevelopment and in Neurodegenerative and Neuropsychiatric Disorders.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
- Non-genetic factors that influence methamphetamine intake in a genetic model of differential methamphetamine consumption.Psychopharmacology · 2020Article
- Using the tools of genetic epidemiology to understand sex differences in neuropsychiatric disorders.Genes, brain, and behavior · 2020Review
- FinnTwin12 Cohort: An Updated Review.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019Review
- Environmental Exposures and Neuropsychiatric Disorders: What Role Does the Gut-Immune-Brain Axis Play?Current environmental health reports · 2018Review
- Shaping vulnerability to addiction - the contribution of behavior, neural circuits and molecular mechanisms.Neuroscience and biobehavioral reviews · 2018Review
- Behavioral and Brain Activity Indices of Cognitive Control Deficits in Binge Drinkers.Brain sciences · 2018Article
- Stress and the Emerging Roles of Chromatin Remodeling in Signal Integration and Stable Transmission of Reversible Phenotypes.Frontiers in behavioral neuroscience · 2017Review
- Genetic influences on adolescent behavior.Neuroscience and biobehavioral reviews · 2016Review
- Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 2. Fundamental Concepts in Genetic Epidemiology.Current psychiatry reviews · 2014Article
- Novel siRNA delivery strategy: a new "strand" in CNS translational medicine?Cellular and molecular life sciences : CMLS · 2014Review
- Transgenic mouse models for ADHD.Cell and tissue research · 2013Review
- Genetics and psychiatry: a proposal for the application of the precautionary principle.Medicine, health care, and philosophy · 2013Article
- Effect of maternal lipopolysaccharide administration on the development of dopaminergic receptors and transporter in the rat offspring.PloS one · 2013Article
- Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression.Archives of general psychiatry · 2012Article
- Towards medication-enhancement of cognitive interventions in schizophrenia.Handbook of experimental pharmacology · 2012Review
- Paternal age and psychiatric disorders: findings from a Dutch population registry.Schizophrenia research · 2011Article
- Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders.Journal of child psychology and psychiatry, and allied disciplines · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both genetic and nongenetic risk factors, as well as interactions and correlations between them, are thought to contribute to the etiology of psychiatric and behavioral phenotypes. Genetic epidemiology consistently supports the involvement of genes in liability. Molecular genetic studies have been less successful in identifying liability genes, but recent progress suggests that a number of specific genes contributing to risk have been identified. Collectively, the results are complex and inconsistent, with a single common DNA variant in any gene influencing risk across human populations. Few specific genetic variants influencing risk have been unambiguously identified, Contemporary approaches, however hold great promise to further elucidate liability genes and variants, as well as their potential inter-relationships with each other and with the environment. We will review the fields of genetic epidemiology and molecular genetics, providing examples from the literature to illustrate the key concepts emerging from this work.
Indexed as
Identifiers
20373663PMC3181950What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.