ArticleCurrent protocols in human genetics2010
Comprehensive high-throughput arrays for relative methylation (CHARM).
Article in Current protocols in human genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Article
- Epigenetic changes in sperm are associated with paternal and child quantitative autistic traits in an autism-enriched cohort.Molecular psychiatry · 2024Article
- Laboratory methods to decipher epigenetic signatures: a comparative review.Cellular & molecular biology letters · 2021Review
- Article
- Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.Environmental health perspectives · 2017Article
- Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis .Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis.Genome medicine · 2016Article
- Single-cell transcriptome and epigenomic reprogramming of cardiomyocyte-derived cardiac progenitor cells.Scientific data · 2016Article
- Methylation profiling identified novel differentially methylated markers including OPCML and FLRT2 in prostate cancer.Epigenetics · 2016Article
- Epigenomic Reprogramming of Adult Cardiomyocyte-Derived Cardiac Progenitor Cells.Scientific reports · 2015Article
- CellMethy: Identification of a focal concordantly methylated pattern of CpGs revealed wide differences between normal and cancer tissues.Scientific reports · 2015Article
- Prenatal mercury concentration is associated with changes in DNA methylation at TCEANC2 in newborns.International journal of epidemiology · 2015Article
- Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort.International journal of epidemiology · 2015Article
- Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes.Cell metabolism · 2015Article
- Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia.Epigenetics · 2015Article
- Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis.American journal of respiratory and critical care medicine · 2014Article
- Epigenetic alterations in depression and antidepressant treatment.Dialogues in clinical neuroscience · 2014Review
- Epigenetic mechanisms and the development of asthma.The Journal of allergy and clinical immunology · 2012Review
- DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth.International journal of epidemiology · 2012Article
- Epigenetic control of gene expression in the lung.American journal of respiratory and critical care medicine · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
DNA methylation (DNAm) is a term used to describe the heritable covalent addition of a methyl group to cytosines at CpG dinucleotides in mammals. While methods for examining DNAm status at specific loci have existed for several years, recent technological advances have begun to enable the examination of DNAm across the genome. In this unit, we describe comprehensive high-throughput arrays for relative methylation (CHARM), a highly sensitive and specific approach to measure DNA methylation across the genome. This method makes no assumptions about where functionally important DNAm occurs, i.e., CpG island or promoter regions, and includes lower-CpG-density regions of the genome. In addition, it uses a novel genome-weighted smoothing algorithm to correct for CpG density and fragment biases present in methyl-enrichment or methyl-depletion DNA-fractionation methods. It can be applied to studying epigenomic changes in DNAm for normal and diseased samples.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.