ArticleCurrent protocols in neuroscience2010
Transfection of mouse cochlear explants by electroporation.
Article in Current protocols in neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Kölliker's Organ Functions as a Developmental Hub in Mouse Cochlea Regulating Spiral Limbus and Tectorial Membrane Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Purinergic Signaling Controls Spontaneous Activity in the Auditory System throughout Early Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- TUB and ZNF532 Promote the Atoh1-Mediated Hair Cell Regeneration in Mouse Cochleae.Frontiers in cellular neuroscience · 2021Article
- GSK3 regulates hair cell fate in the developing mammalian cochlea.Developmental biology · 2019Article
- Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development.Developmental dynamics : an official publication of the American Association of Anatomists · 2018Article
- CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.The Journal of experimental medicine · 2018Article
- Mapping of bionic array electric field focusing in plasmid DNA-based gene electrotransfer.Gene therapy · 2016Article
- Round window membrane intracochlear drug delivery enhanced by induced advection.Journal of controlled release : official journal of the Controlled Release Society · 2014Article
- The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.Developmental biology · 2013Article
- Gene transfer in inner ear cells: a challenging race.Gene therapy · 2013Review
- TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1.Developmental biology · 2012Article
- MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro.PloS one · 2012Article
- Improved biolistic transfection of hair cells.PloS one · 2012Article
- Cell type-specific transcriptome analysis reveals a major role for Zeb1 and miR-200b in mouse inner ear morphogenesis.PLoS genetics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The sensory epithelium of the mammalian inner ear, also referred to as the organ of Corti, is a remarkable structure comprised of highly ordered rows of mechanosensory hair cells and non-sensory supporting cells located within the coiled cochlea. This unit describes an in vitro explant culture technique that can be coupled with gene transfer via electroporation to study the effects of altering gene expression during development of the organ of Corti. While the protocol is largely focused on embryonic cochlea, the same basic protocol can be used on cochleae from mice as old as P5.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.