ArticleHepatology (Baltimore, Md.)2010
Hemochromatosis gene (HFE) mutations and cancer risk: expanding the clinical manifestations of hereditary iron overload.
Article in Hepatology (Baltimore, Md.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- C282Y polymorphism in the HFE gene is associated with risk of breast cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013Pooled it
- HFE gene C282Y variant is associated with colorectal cancer in Caucasians: a meta-analysis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013Pooled it
- A randomized trial of iron depletion in patients with nonalcoholic fatty liver disease and hyperferritinemia.World journal of gastroenterology · 2014Trial
- Article
- Iron overload in HFE-related hemochromatosis severely impairs Vδ2+ γδ T-cell homeostasis.Blood · 2025Article
- The Emerging Role of Tumor Microenvironmental Stimuli in Regulating Metabolic Rewiring of Liver Cancer Stem Cells.Cancers · 2022Review
- Investigation of the effects of overexpression of jumping translocation breakpoint (JTB) protein in MCF7 cells for potential use as a biomarker in breast cancer.American journal of cancer research · 2022Article
- Iron at the Interface of Hepatocellular Carcinoma.International journal of molecular sciences · 2021Review
- Crosstalk between Macrophages, T Cells, and Iron Metabolism in Tumor Microenvironment.Oxidative medicine and cellular longevity · 2021Review
- Iron: An Essential Element of Cancer Metabolism.Cells · 2020Review
- Iron: The cancer connection.Molecular aspects of medicine · 2020Review
- Hepatocellular carcinoma in adult thalassemia patients: an expert opinion based on current evidence.BMC gastroenterology · 2020Review
- Iron Metabolism in Cancer Progression.International journal of molecular sciences · 2020Review
- Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study.Nutrients · 2020Article
- Diagnosis and Treatment of GeneticGastroenterology research · 2019Review
- Iron and Cancer.Annual review of nutrition · 2018Review
- The Prevalence and Implication of Zinc Deficiency in Patients With Chronic Liver Disease.Journal of clinical medicine research · 2018Article
- The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system.Immunity, inflammation and disease · 2017Review
- Beyond Human Leukocyte Antigen Class I Antigens: Hereditary Hemochromatosis Gene Mutations in Recurrent Aphthous Oral Ulcers and Behçet Disease in the South of Tunisia.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2017Article
- Gender and plasma iron biomarkers, but not HFE gene mutations, increase the risk of colorectal cancer and polyps.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
20373367What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.