ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2010
The accuracy of sentinel node mapping according to T stage in patients with gastric cancer.
Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Sentinel Lymph Node Biopsy in Gastric Cancer, an Optimization of Imaging Protocol for Tracer Mapping.World journal of surgery · 2021Pooled it
- Sentinel Node Navigation Surgery for Upper Gastrointestinal Malignancies: Current Status, Clinical Significance, and Future Perspectives.Magyar onkologia · 2026Review
- Fluorescence Guided Surgery in Gastric Cancer: What Do We Have and What Can We Do?Annals of gastroenterological surgery · 2025Review
- Indocyanine green and near-infrared fluorescence-guided surgery for gastric cancer: a narrative review.Journal of minimally invasive surgery · 2024Review
- Endoscopic fluorescent lymphography for gastric cancer.World journal of gastrointestinal endoscopy · 2023Review
- Tracers in Gastric Cancer Surgery.Cancers · 2022Review
- Techniques and Current Role of Sentinel Lymph Node (SLN) Concept in Gastric Cancer Surgery.Frontiers in surgery · 2018Review
- Sentinel node navigation in gastric cancer: new horizons for personalized minimally invasive surgical oncology?Translational gastroenterology and hepatology · 2016Review
- Sentinel node navigation surgery for gastric cancer: Overview and perspective.World journal of gastrointestinal surgery · 2015Review
- Sentinel node navigation surgery in gastric cancer: Current status.World journal of gastrointestinal surgery · 2014Review
- Accurate, safe, and rapid method of intraoperative tumor identification for totally laparoscopic distal gastrectomy: injection of mixed fluid of sodium hyaluronate and patent blue.Surgical endoscopy · 2014Article
- Tumor differentiation as related to sentinel lymph node status in gastric cancer.World journal of gastrointestinal surgery · 2014Article
- Incidence trends and mortality rates of gastric cancer in Israel.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2013Article
- Evaluation of focused sentinel lymph node RT-qPCR screening for micrometastases with the use of the Maruyama computer program.European surgery : ACA : Acta chirurgica Austriaca · 2013Article
- Sentinel lymph node biopsy for gastric cancer: Where do we stand?World journal of gastrointestinal surgery · 2011Article
- Overt bone metastasis and bone marrow micrometastasis of early gastric cancer.Surgery today · 2011Review
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9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSentinel lymph node (SLN) mapping has been recently introduced to the field of gastric cancer. To the best of our knowledge, no study has dealt with the accuracy of SLN mapping according to the T stage of the primary tumor. The aim of the present study was to evaluate SLN status according to the T stage of the primary tumors.
methodsEighty patients with gastric cancer underwent SLN mapping with patent blue dye during gastric resection.
resultsForty-seven patients underwent distal subtotal gastrectomy; 17 patients, proximal gastrectomy; 14, total gastrectomy; and 2, gastric stump resection. SLNs were stained in 61/80 patients (76.3%). The number of stained SLNs varied from 1 to 16 (mean, 3.3). Patients undergoing proximal gastrectomy had a mean of 3 stained SLNs, whereas patients undergoing distal subtotal gastrectomy had a mean of 2.8 stained SLNs. In 55/61 patients (90.2%) with stained SLNs a positive correlation was found between the presence of metastases and stained or non-stained SLNs. Ten out of 11 patients (90.9%) with T1 tumors (mean, 3.27 SLNs per patient) and 15/17 patients with T2 tumors (88.2%; mean, 3 SLNs per patient) had stained SLNs as compared to only 33/48 (68.8%) of patients with T3 tumors (mean, 3.3 SLNs per patient). The positive predictive value of the SLN mapping was 100%, the negative predictive value was 76.9%, and sensitivity was 85.4%.
conclusionWhile in T1 and T2 tumors sentinel node mapping may be of assistance in the decision-making process regarding the extent of lymphadenectomy (sensitivity, 100%; negative predictive value, 90%-100%), SLN mapping in patients with T3 tumors will be misleading in a third of the patients and should not be attempted.
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