ArticleWorld journal of surgery2010
Clinical and imaging assessment of cervical lymph node metastasis in papillary thyroid carcinomas.
Article in World journal of surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 5 of them syntheses that pooled it.
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Who cites it
71 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Guideline for the Surgical Management of Locally Invasive Differentiated Thyroid Cancer From the Korean Society of Head and Neck Surgery.Clinical and experimental otorhinolaryngology · 2023Guideline
- Pooled it
- Diagnostic values of F-18 FDG PET or PET/CT, CT, and US for Preoperative Lymph Node Staging in Thyroid Cancer: A Network Meta-Analysis.The British journal of radiology · 2021Pooled it
- Diagnostic performance of CT in detection of metastatic cervical lymph nodes in patients with thyroid cancer: a systematic review and meta-analysis.European radiology · 2019Pooled it
- Performance of CT in the Preoperative Diagnosis of Cervical Lymph Node Metastasis in Patients with Papillary Thyroid Cancer: A Systematic Review and Meta-Analysis.AJNR. American journal of neuroradiology · 2017Pooled it
- The prognostic value of central excised lymph node count in N1a papillary thyroid cancer: a population-based study.Gland surgery · 2026Article
- Radiomics-Based machine learning for preoperative prediction of Large-Number central lymph node metastasis in papillary thyroid carcinoma.Endocrine · 2026Article
- Article
- Development and validation of a prediction model for lymph node metastasis in thyroid cancer: integrating deep learning and radiomics features from intra- and peri-tumoral regions.Gland surgery · 2025Article
- Enhancement on CT for preoperative diagnosis of metastatic lymph nodes in thyroid cancer: a comparison across experience levels.European radiology · 2025Article
- Is conservative treatment always safe in unifocal clinically T1a/node-negative papillary thyroid carcinoma?World journal of surgery · 2025Article
- Predictive Values of Clinical Features and Multimodal Ultrasound for Central Lymph Node Metastases in Papillary Thyroid Carcinoma.Diagnostics (Basel, Switzerland) · 2024Review
- Carbon nanoparticles beneficial for prophylactic central compartment lymph node dissection in cN0 papillary thyroid carcinoma.Heliyon · 2024Article
- Risk nomogram for papillary thyroid microcarcinoma with central lymph node metastasis and postoperative thyroid function follow-up.Frontiers in endocrinology · 2024Article
- BCL9 is a Risk Factor of Neck Lymph Nodes Metastasis and Correlated with Immune Cell Infiltration in Papillary Thyroid Carcinoma.International journal of general medicine · 2024Article
- Prediction of cervical lymph node metastasis in solitary papillary thyroid carcinoma based on ultrasound radiomics analysis.Frontiers in oncology · 2024Article
- Clinical features and imaging examination assessment of cervical lymph nodes for thyroid carcinoma.BMC cancer · 2023Article
- A model for predicting lymph node metastasis of thyroid carcinoma: a multimodality convolutional neural network study.Quantitative imaging in medicine and surgery · 2023Article
- PTC-MAS: A Deep Learning-Based Preoperative Automatic Assessment of Lymph Node Metastasis in Primary Thyroid Cancer.Diagnostics (Basel, Switzerland) · 2023Article
- Role of computed tomography in the evaluation of regional metastasis in well-differentiated thyroid cancer.Frontiers in radiology · 2023Article
11 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe goals of this study were to analyze clinical factors that affect cervical lymph node metastasis (LNM) in papillary thyroid cancer (PTC), and to evaluate the diagnostic accuracy of preoperative ultrasound (US) and computed tomography (CT) of the neck.
methodsThe study sample included 589 consecutive patients who underwent surgery for PTC. Patient age and sex, number, size, and location of tumors, lymphovascular invasion, and extrathyroidal extension were evaluated as risk factors for central and lateral LNM.
resultsIncreased risk of lymph node metastasis was found for male patients, <45 years old, with tumor size >1 cm, lymphovascular invasion, and extrathyroidal invasion. Cancers located in the upper neck had a higher relative risk of lateral metastasis than cancers located in the lower neck. Sensitivity of both US and CT imaging was higher for lateral (70-80%) than for central (42-47%) LNM. Specificity of US and CT was high (92-97%) for both central and lateral LNM. Using central lymph node size of greater than 5 mm as an indicator of metastasis, preoperative US had 58.3% sensitivity and 71.4% specificity.
conclusionsPreoperative US and CT imaging are useful for identifying features that indicate a high risk of LNM and for determining appropriate management of PTC.
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