ArticleJournal of theoretical biology2010
The rules of variation: amino acid exchange according to the rotating circular genetic code.
Article in Journal of theoretical biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- A cryptic START domain regulates deeply conserved transcription factors.The Plant cell · 2026Article
- Mitogenomic Insights into Orthocladiinae (Diptera: Chironomidae): Structural Diversity and Phylogenetic Implications.Biology · 2025Article
- A novel missense variant in endothelin-2 (EDN2) causes a growth and respiratory lethal syndrome in bovine.Animal genetics · 2022Article
- paPAML: An Improved Computational Tool to Explore Selection Pressure on Protein-Coding Sequences.Genes · 2022Article
- Seventeen Ustilaginaceae High-Quality Genome Sequences Allow Phylogenomic Analysis and Provide Insights into Secondary Metabolite Synthesis.Journal of fungi (Basel, Switzerland) · 2022Article
- Article
- Decoding the Role of DVL1 in Intracranial Meningioma.International journal of molecular sciences · 2021Article
- Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses.International journal of molecular sciences · 2020Article
- A large intragenic deletion in the CLCN1 gene causes Hereditary Myotonia in pigs.Scientific reports · 2019Article
- Genomic coordinates and continental distribution of 120 blood group variants reported by the 1000 Genomes Project.Transfusion · 2018Article
- Codon based co-occurrence network motifs in human mitochondria.Scientific reports · 2018Article
- A Tetrahedral Representation of the Genetic Code Emphasizing Aspects of Symmetry.BIO-complexity · 2012Article
- Escaping the cut by restriction enzymes through single-strand self-annealing of host-edited 12-bp and longer synthetic palindromes.DNA and cell biology · 2012Article
- Defragged Binary I Ching Genetic Code Chromosomes Compared to Nirenberg's and Transformed into Rotating 2D Circles and Squares and into a 3D 100% Symmetrical Tetrahedron Coupled to a Functional One to Discern Start From Non-Start Methionines through a Stella Octangula.Journal of proteome science and computational biology · 2012Article
- Most Used Codons per Amino Acid and per Genome in the Code of Man Compared to Other Organisms According to the Rotating Circular Genetic Code.NeuroQuantology : an interdisciplinary journal of neuroscience and quantum physics · 2011Article
- The Quantum Workings of the Rotating 64-Grid Genetic Code.NeuroQuantology : an interdisciplinary journal of neuroscience and quantum physics · 2011Article
- The Rules of Variation Expanded, Implications for the Research on Compatible Genomics.Biosemiotics · 2011Article
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1 author.
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Abstract
General guidelines for the molecular basis of functional variation are presented while focused on the rotating circular genetic code and allowable exchanges that make it resistant to genetic diseases under normal conditions. The rules of variation, bioinformatics aids for preventative medicine, are: (1) same position in the four quadrants for hydrophobic codons, (2) same or contiguous position in two quadrants for synonymous or related codons, and (3) same quadrant for equivalent codons. To preserve protein function, amino acid exchange according to the first rule takes into account the positional homology of essential hydrophobic amino acids with every codon with a central uracil in the four quadrants, the second rule includes codons for identical, acidic, or their amidic amino acids present in two quadrants, and the third rule, the smaller, aromatic, stop codons, and basic amino acids, each in proximity within a 90 degree angle. I also define codifying genes and palindromati, CTCGTGCCGAATTCGGCACGAG.
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