GuidelineCritical care (London, England)2010
Management of bleeding following major trauma: an updated European guideline.
Guideline in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 191 papers, 11 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
191 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Arterial angioembolisation versus pre-peritoneal pelvic packing in haemodynamically unstable patients with complex pelvic fractures: a meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Pooled it
- A systematic review on the rotational thrombelastometry (ROTEM®) values for the diagnosis of coagulopathy, prediction and guidance of blood transfusion and prediction of mortality in trauma patients.Scandinavian journal of trauma, resuscitation and emergency medicine · 2016Pooled it
- [Complex pelvic traumas : data linkage of the German Pelvic Injury Register and the TraumaRegister DGU®].Der Unfallchirurg · 2015Pooled it
- Fibrinogen concentrate in bleeding patients.The Cochrane database of systematic reviews · 2013Pooled it
- Management of bleeding and coagulopathy following major trauma: an updated European guideline.Critical care (London, England) · 2013Pooled it
- [Dealing with massive bleeding and associated perioperative coagulopathy: recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine].Der Anaesthesist · 2013Guideline
- Acute traumatic coagulopathy in severe injury: incidence, risk stratification, and treatment options.Deutsches Arzteblatt international · 2011Pooled it
- Coagulation management in multiple trauma: a systematic review.Intensive care medicine · 2011Pooled it
- Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review.Critical care (London, England) · 2011Pooled it
- The acute management of trauma hemorrhage: a systematic review of randomized controlled trials.Critical care (London, England) · 2011Pooled it
- Guideline
- Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the FEISTY trial.Critical care (London, England) · 2022Trial
- Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.PloS one · 2020Trial
- The effect of fibrinogen concentrate and factor XIII on thromboelastometry in 33% diluted blood with albumin, gelatine, hydroxyethyl starch or saline in vitro.Blood transfusion = Trasfusione del sangue · 2013Trial
- Impact of experimental haemodilution on platelet function, thrombin generation and clot firmness: effects of different coagulation factor concentrates.Blood transfusion = Trasfusione del sangue · 2013Trial
- Promoting advance planning for health care and research among older adults: a randomized controlled trial.BMC medical ethics · 2012Trial
- Letter to the Editor: Implementing ESR Essentials for trauma care-challenges and opportunities from a Latin American perspective.European radiology · 2026Article
- Article
- Study on the preparation of multifunctional bacterial cellulose-based wound dressings and their in vitro hemostatic performance.Scientific reports · 2026Article
- Validation of a Wearable Photoplethysmography-Based Sensor for Compensatory Reserve Measurement Monitoring in Simulated Human Hemorrhage.Sensors (Basel, Switzerland) · 2026Article
131 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEvidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes.
methodsThe multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature.
resultsKey changes encompassed in this version of the guideline include new recommendations on coagulation support and monitoring and the appropriate use of local haemostatic measures, tourniquets, calcium and desmopressin in the bleeding trauma patient. The remaining recommendations have been reevaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies.
conclusionsThis guideline provides an evidence-based multidisciplinary approach to the management of critically injured bleeding trauma patients.
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