ArticleThe Journal of the Acoustical Society of America2010
Distortion product emissions from a cochlear model with nonlinear mechanoelectrical transduction in outer hair cells.
Article in The Journal of the Acoustical Society of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 85 citations in OpenAlex.
- Broad nonlinearity in reticular lamina vibrations requires compliant organ of Corti structures.Biophysical journal · 2023Article
- Link between stimulus otoacoustic emissions fine structure peaks and standing wave resonances in a cochlear model.The Journal of the Acoustical Society of America · 2022Article
- Intracochlear distortion products are broadly generated by outer hair cells but their contributions to otoacoustic emissions are spatially restricted.Scientific reports · 2021Article
- Measuring Distortion-Product Otoacoustic Emission With a Single Loudspeaker in the Ear: Stimulus Design and Signal Processing Techniques.Frontiers in digital health · 2021Article
- A canonical oscillator model of cochlear dynamics.Hearing research · 2019Article
- Constraints imposed by zero-crossing invariance on cochlear models with two mechanical degrees of freedom.The Journal of the Acoustical Society of America · 2019Article
- Power Dissipation in the Cochlea Can Enhance Frequency Selectivity.Biophysical journal · 2019Article
- Probing hair cell's mechano-transduction using two-tone suppression measurements.Scientific reports · 2019Article
- An analytic physically motivated model of the mammalian cochlea.The Journal of the Acoustical Society of America · 2019Article
- Modeling the dependence of the distortion product otoacoustic emission response on primary frequency ratio.Journal of the Association for Research in Otolaryngology : JARO · 2018Article
- A FPGA Implementation of the CAR-FAC Cochlear Model.Frontiers in neuroscience · 2018Article
- Modeling Pitch Perception With an Active Auditory Model Extended by Octopus Cells.Frontiers in neuroscience · 2018Article
- Modeling signal propagation in the human cochlea.The Journal of the Acoustical Society of America · 2017Article
- Two passive mechanical conditions modulate power generation by the outer hair cells.PLoS computational biology · 2017Article
- Analytical and numerical modeling of the hearing system: Advances towards the assessment of hearing damage.Hearing research · 2017Review
- Article
- The importance of the hook region of the cochlea for bone-conduction hearing.Biophysical journal · 2014Article
- Modelling cochlear mechanics.BioMed research international · 2014Review
- Detection of cochlear amplification and its activation.Biophysical journal · 2013Article
- Superior-semicircular-canal dehiscence: effects of location, shape, and size on sound conduction.Hearing research · 2013Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
A model of cochlear mechanics is described in which force-producing outer hair cells (OHC) are embedded in a passive cochlear partition. The OHC mechanoelectrical transduction current is nonlinearly modulated by reticular-lamina (RL) motion, and the resulting change in OHC membrane voltage produces contraction between the RL and the basilar membrane (BM). Model parameters were chosen to produce a tonotopic map typical of a human cochlea. Time-domain simulations showed compressive BM displacement responses typical of mammalian cochleae. Distortion product (DP) otoacoustic emissions at 2f(1)-f(2) are plotted as isolevel contours against primary levels (L(1),L(2)) for various primary frequencies f(1) and f(2) (f(1)<f(2)). The L(1) at which the DP reaches its maximum level increases as L(2) increases, and the slope of the "optimal" linear path decreases as f(2)/f(1) increases. When primary levels and f(2) are fixed, DP level is band passed against f(1). In the presence of a suppressor, DP level generally decreases as suppressor level increases and as suppressor frequency gets closer to f(2); however, there are exceptions. These results, being similar to data from human ears, suggest that the model could be used for testing hypotheses regarding DP generation and propagation in human cochleae.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.