Coeloglossum viride var. bracteatum extract protects against amyloid toxicity in rat prefrontal cortex neurons.

Xiao-Yan Qin, Jia Cui, Yan Zhang

Open access · greenAbstract read

In one paragraph

Article in International journal of clinical and experimental medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

0.4field-weighted citation impact, top 29% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

Heliyon · 2021
Article
Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS.Molecules (Basel, Switzerland) · 2020
Article
Neuroprotective effects of a Coeloglossum viride var. Bracteatum extract in vitro and in vivo.Scientific reports · 2017
Article
Investigation on effects of the nourishing kidney and eliminating toxicity decoction on immunological imbalance of Th1, Th17 and Treg in HBV transgenic mice.International journal of clinical and experimental medicine · 2015
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiao-Yan QinLaboratory of Biotechnology and State Key Laboratory of Chinese ethnic minority traditional medicine, College of Life & Environmental Science, Minzu University of China Beijing, 100081, China Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University Beijing, 100871, China.

Jia Cui

Yan Zhang

Minzu University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CE is the extract from Coeloglossum viride var.bracteatum, a plant widely used as a traditional medicine in the Southwest China, such as Tibet. The effects of CE against amyloid toxicity in cell culture were examined in the present study. The results indicate that CE can protect against amyloid beta (Abeta)(25-35)-induced cytotoxicity in rat primary prefrontal cortex neurons. Bcl(2) and Csp3 activation may be involved in CE protection. CE could be a promising candidate for amyloid-based Alzheimer's disease (AD) prevention or therapy.

Indexed as

Alzheimer's diseaseAmyloid βCECoeloglossum viride var.bracteatumtraditional Chinese medicine

Identifiers

PMID20369044

PMCPMC2848310

OpenAlexW269405971

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.