Evidence map›Paper›PMID 20368481›Full record

Trial reportArchives of pediatrics & adolescent medicine2010

Growth and associations between auxology, caregiving environment, and cognition in socially deprived Romanian children randomized to foster vs ongoing institutional care.

Dana E Johnson, Donald Guthrie, Anna T Smyke, Sebastian F Koga, Nathan A Fox, Charles H Zeanah, Charles A Nelson

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of pediatrics & adolescent medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
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  8. Social communication difficulties and autism in previously institutionalized children.Journal of the American Academy of Child and Adolescent Psychiatry · 2015
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  18. Does rapid rebound height growth come at a neurocognitive cost for previously institutionalized youth?Journal of child psychology and psychiatry, and allied disciplines · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Dana E JohnsonDepartment of Pediatrics, Division of Neonatology, 420 Delaware St SE, Minneapolis, MN 55455, USA. johns008@umn.edu
Donald Guthrie
Anna T Smyke
Sebastian F Koga
Nathan A Fox
Charles H Zeanah
Charles A Nelson
Harvard University Press · USTulane University · USTwin Cities Orthopedics · USUniversity of California, Los Angeles · USUniversity of Maryland, College Park · USUniversity of Virginia · US

Funding

The Relation Between Early Psychosocial Deprivation and Mental Health at 12 YearsR01MH091363 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A, NELSON, CHARLES ALEXANDER · 2010 to 2024
$9.2M
NIMH NIH HHS R01 MH091363
6 · The paper itself

Abstract

objectivesTo determine effects of improved nurturing compared with institutional care on physical growth and to investigate the association between growth and cognitive development.

designA randomized controlled trial beginning in infants (mean age, 21.0 months; range, 5-32 months), with follow-up at 30, 42, and 54 months of age.

settingInstitutionalized and community children in Bucharest, Romania.

participantsOne hundred thirty-six healthy institutionalized children from 6 orphanages and 72 typically developing, never-institutionalized children.

interventionInstitutionalized children were randomly assigned to receive foster care or institutional care as usual. OUTCOME MEASURES: Auxology and measures of intelligence over time.

resultsGrowth in institutionalized children was compromised, particularly in infants weighing less than 2500 g at birth. Mean height and weight, though not head size, increased to near normal within 12 months in foster care. Significant independent predictors for greater catch-up in height and weight included age younger than 12 months at randomization, lower baseline z scores, and higher caregiving quality, particularly caregiver sensitivity and positive regard. Baseline developmental quotient, birth weight, and height catch-up were significant independent predictors of cognitive abilities at follow-up. Each incremental increase of 1 in standardized height scores between baseline and 42 months was associated with a mean increase of 12.6 points (SD, 4.7 points) in verbal IQ (P < .05).

conclusionsFoster care had a significant effect on growth, particularly with early placement and high-quality care. Growth and IQ in low-birth-weight children are particularly vulnerable to social deprivation. Catch-up growth in height under more nurturing conditions is a useful indicator of caregiving quality and cognitive improvement.

Indexed as

Child, InstitutionalizedFoster Home CareGrowth DisordersSocial IsolationAnthropometryCaregiversChild, PreschoolCognitionFemaleFollow-Up StudiesHumansInfantMaleOrphanagesRomania

Identifiers

PMID20368481
PMCPMC4126580
OpenAlexW2153358224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.