ArticlePsychosomatic medicine2010
Tendency to angry rumination predicts stress-provoked endothelin-1 increase in patients with coronary artery disease.
Article in Psychosomatic medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study.Journal of the American Heart Association · 2024Trial
- Cognitive-emotional associations between non-restorative sleep and erectile dysfunction: the role of rumination profiles and resilience.Sexual medicine · 2026Article
- Psychological factors and blood pressure responses to acute stress in women with takotsubo syndrome: an exploratory study.European journal of cardiovascular nursing · 2025Article
- Acute Pressor Response to Psychosocial Stress Is Dependent on Endothelium-Derived Endothelin-1.Journal of the American Heart Association · 2018Article
- Rumination in migraine: Mediating effects of brooding and reflection between migraine and psychological distress.Psychology & health · 2016Article
- Post-traumatic Stress Disorder and Cardiovascular Disease.Current cardiology reports · 2016Review
- Body Mass Index and Risk for Mental Stress Induced Ischemia in Coronary Artery Disease.Molecular medicine (Cambridge, Mass.) · 2016Article
- Angiotensin II is required to induce exaggerated salt sensitivity in Dahl rats exposed to maternal separation.Physiological reports · 2015Article
- Anger is associated with increased IL-6 stress reactivity in women, but only among those low in social support.International journal of behavioral medicine · 2014Article
- Confluence of depression and acute psychological stress among patients with stable coronary heart disease: effects on myocardial perfusion.Journal of the American Heart Association · 2014Article
- Hostility, health behaviors, and risk of recurrent events in patients with stable coronary heart disease: findings from the Heart and Soul Study.Journal of the American Heart Association · 2013Article
- How mental stress affects endothelial function.Pflugers Archiv : European journal of physiology · 2011Review
- Depression predicts elevated endothelin-1 in patients with coronary artery disease.Psychosomatic medicine · 2011Article
- Endothelin-1 release and stimulation of the inflammatory cascade: is acute coronary syndrome triggered by watching spectator sports?Journal of the American College of Cardiology · 2010Article
- hsCRP and ET-1 expressions in patients with no-reflow phenomenon after Percutaneous Coronary Intervention.Pakistan journal of medical sciencesArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine whether a tendency to angry rumination predicts anger recall (AR) stress-provoked increase in endothelin (ET)-1 among patients with coronary heart disease (CHD).
methodsPatients with chronic stable CHD (n = 105) completed a five-item measure of tendency to angry rumination (DAB-VR) and underwent a laboratory AR stress protocol (15-minute resting baseline [BL], 8-minute AR). Blood samples drawn at end of BL and AR were assayed for ET-1. Change in ET-1 from BL to AR (increase versus decrease/no change) was treated dichotomously in multivariate logistic regression models, including DAB-VR score and potential confounders, to evaluate the contribution of DAB-VR to the prediction of change in ET-1.
resultsIn the multivariate model, DAB-VR score significantly predicted ET-1 increase (odds ratio, 1.34; 95% confidence interval, 1.10-1.1.63; p = .004), controlling for age, history of diabetes, hypercholesterolemia, rate pressure product, use of beta blockers, and statins.
conclusionsA tendency to angry rumination independently predicted AR stress-provoked ET-1 increase among patients with CHD. Given the involvement of ET-1 in plaque rupture, anger rumination tendency may identify vulnerability to anger-triggered acute coronary syndrome through prolongation of initial anger mobilization. The contribution of ruminative thinking to sustained poststress ET-1 elevation and the synergistic relationship of ET-1 during emotional stress with norepinephrine and nitric oxide remain to be explored.
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