ReviewJournal of neuroendocrinology2010
Nongenomic actions of adrenal steroids in the central nervous system.
Review in Journal of neuroendocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 76 citations in OpenAlex.
- Proteomic analysis of central amygdala systems regulated by mifepristone in the context of alcohol dependence.Neuropharmacology · 2026Article
- St. John's Wort for Depression: From Neurotransmitters to Membrane Plasticity.International journal of molecular sciences · 2025Review
- Understanding stress-induced illegitimate aggression: the role of physiological and psychological factors in police cadets.Biologia futura · 2025Article
- Cardiovascular disease and depression: a bidirectional relationship and its clinical implications.Frontiers in psychiatry · 2025Review
- HPA Axis in the Pathomechanism of Depression and Schizophrenia: New Therapeutic Strategies Based on Its Participation.Brain sciences · 2021Review
- Cortisol on Circadian Rhythm and Its Effect on Cardiovascular System.International journal of environmental research and public health · 2021Review
- The hypothalamic-pituitary-adrenal axis as a substrate for stress resilience: Interactions with the circadian clock.Frontiers in neuroendocrinology · 2020Review
- Role of corticosterone in altered neurobehavioral responses to acute stress in a model of compromised hypothalamic-pituitary-adrenal axis function.Psychoneuroendocrinology · 2019Article
- Rapid Intracellular ZnMolecular neurobiology · 2019Article
- Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility.Stress (Amsterdam, Netherlands) · 2018Review
- A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications.Frontiers in behavioral neuroscience · 2018Review
- Dynamic Regulation of AMPAR Phosphorylation In Vivo Following Acute Behavioral Stress.Cellular and molecular neurobiology · 2016Article
- Metabotropic glutamate receptor-mediated signaling dampens the HPA axis response to restraint stress.Physiology & behavior · 2015Article
- Cortisone and hydrocortisone inhibit human Kv1.3 activity in a non-genomic manner.Naunyn-Schmiedeberg's archives of pharmacology · 2015Article
- FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice.Molecular and cellular endocrinology · 2014Article
- Stress and neurodevelopmental processes in the emergence of psychosis.Neuroscience · 2013Review
- Glucocorticoid receptors are localized to dendritic spines and influence local actin signaling.Molecular neurobiology · 2012Article
- Tune it down to live it up? Rapid, nongenomic effects of cortisol on the human brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- The molecular physiology of CRH neurons.Frontiers in neuroendocrinology · 2012Article
- Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Mineralocorticoids and glucocorticoids are steroid hormones that are released by the adrenal cortex in response to stress and hydromineral imbalance. Historically, adrenocorticosteroid actions are attributed to effects on gene transcription. More recently, however, it has become clear that genome-independent pathways represent an important facet of adrenal steroid actions. These hormones exert nongenomic effects throughout the body, although a significant portion of their actions are specific to the central nervous system. These actions are mediated by a variety of signalling pathways, and lead to physiologically meaningful events in vitro and in vivo. We review the nongenomic effects of adrenal steroids in the central nervous system at the levels of behaviour, neural system activity, individual neurone activity and subcellular signalling activity. A clearer understanding of adrenal steroid activity in the central nervous system will lead to a better ability to treat human disease as well as reduce the side-effects of the steroid treatments already in use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.