ArticleInternational archives of occupational and environmental health2011
Closer correlation of cadmium in urine than that of cadmium in blood with tubular dysfunction markers in urine among general women populations in Japan.
Article in International archives of occupational and environmental health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Current Levels of Environmental Exposure to Cadmium in Industrialized Countries as a Risk Factor for Kidney Damage in the General Population: A Comprehensive Review of Available Data.International journal of molecular sciences · 2023Review
- LncRNA-ENST00000446135 is a novel biomarker of cadmium toxicity in 16HBE cells, rats, and Cd-exposed workers and regulates DNA damage and repair.Toxicology research · 2020Article
- Lead, Mercury, and Cadmium Exposure in the Korean General Population.Journal of Korean medical science · 2018Article
- LncRNA-MALAT1 as a novel biomarker of cadmium toxicity regulates cell proliferation and apoptosis.Toxicology research · 2017Article
- Article
- Long non-coding RNAs as novel expression signatures modulate DNA damage and repair in cadmium toxicology.Scientific reports · 2015Article
- Blood translation elongation factor-1δ is a novel marker for cadmium exposure.International journal of molecular sciences · 2013Article
- Effect of Pregnancy on the Levels of Blood Cadmium and Lead: analysis of 2006-2011 Nanjing Maternity and Child Health Care Hospital Survey Data.Iranian journal of public health · 2013Article
- The association between urinary kidney injury molecule 1 and urinary cadmium in elderly during long-term, low-dose cadmium exposure: a pilot study.Environmental health : a global access science source · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objectives of the present study are to investigate whether cadmium in blood (Cd-B) and cadmium in urine (Cd-U) correlate with each other irrespective of age among general populations and which one of Cd-B or Cd-U correlates more closely with three renal tubular dysfunction markers in urine of α₁-microglobulin (α₁-MG-U), β₂-microglobulin (β₂-MG-U) and N-acetyl-β-D-glucosaminidase (NAG-U).
methodsData on two exposure markers (Cd-B and Cd-U) and three effect markers (α₁-MG-U, β₂-MG-U and NAG-U) were collected for 1,403 adult women in non-polluted areas all over Japan. Possible significance of correlation between the parameters and dependency on age was examined by simple and multiple regression analysis.
resultsBoth Cd-B and Cd-U increased as a function of age. The two exposure markers correlated significantly with each other, and the Cd-U over Cd-B ratio also increased as a function of age. Although both Cd-B and Cd-U correlated significantly with the three effect markers, the correlation was closer for Cd-U than for Cd-B.
conclusionsCd-U rather than Cd-B should be recommended as an exposure marker of choice in Cd biological monitoring of general populations. Effects of aging should be taken into account when evaluating study results.
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