Evidence map›Paper›PMID 20363170›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2010

Abdominal tuberculosis: sonographic diagnosis and treatment response in HIV-positive adults in rural South Africa.

Tom Heller, Sam Goblirsch, Claudia Wallrauch, Richard Lessells, Enrico Brunetti

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
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  6. Article
  7. Review
  8. Point-of-Care Ultrasound for Tropical Disease: Implications for Clinical Decision-Making.The American journal of tropical medicine and hygiene · 2020
    Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Ultrasonography of peritoneal tuberculosis.Journal of ultrasonography · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Tom HellerHlabisa Hospital, Hlabisa, KwaZulu-Natal, South Africa.
Sam Goblirsch
Claudia Wallrauch
Richard Lessells
Enrico Brunetti
University of KwaZulu-Natal · ZAHlabisa Hospital · ZAUniversity of Minnesota · USUniversity of Pavia · IT

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveTo investigate the diagnostic value of abdominal ultrasound in HIV-positive inpatients in a rural African setting.

methodsThis was a prospective case series over 3 months of adult HIV-positive patients with symptoms suggestive of abdominal tuberculosis (TB). Diagnostic ultrasound was performed for all patients: sonographic criteria included abdominal lymph node enlargement (>1.5cm) and focal splenic lesions; ascites was a supportive finding. Further diagnostic studies, e.g., aspiration or biopsy were not routinely performed. TB treatment was initiated on the basis of clinical and sonographic features. The patients were contacted after 4 months to evaluate the clinical outcome.

resultsOne hundred and eighty adult HIV-positive patients were screened; 30 (16.7%) showed sonographic signs of abdominal TB. The median CD4 count was 78 cells/mm(3). Presenting symptoms were weight loss (86.7%), abdominal pain (76.7%), and diarrhea (60%). Abdominal lymph node enlargement was the diagnostic finding in almost all cases (96.7%); hypoechoic lesions of the spleen were seen in 50% and ascites in 73.3%. Follow-up information was available for 25 patients: 24% had died and the remaining 76% reported symptomatic improvement and weight gain.

conclusionsCharacteristic sonographic features of abdominal TB are common in HIV-infected inpatients in a rural African setting. Ultrasound should be introduced into clinical algorithms for the diagnosis of extrapulmonary TB.

Indexed as

AdultAscitesFemaleHIV InfectionsHumansLymphatic DiseasesMaleMiddle AgedProspective StudiesRural PopulationSouth AfricaSpleenTuberculosis, GastrointestinalUltrasonographyYoung Adult

Identifiers

PMID20363170
PMCPMC2954310
OpenAlexW2024969595

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.