Evidence map›Paper›PMID 20361365›Full record

ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2010

[Replacement of infected knee and hip endoprostheses].

M Militz, V Bühren

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Infections of hip and knee endoprostheses. Spectrum of pathogens and the role of multiresistant bacteria].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016
    Article
  5. Outcome of total knee replacement following explantation and cemented spacer therapy.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2016
    Article
  6. [Diagnosis of periprosthetic hip infections].Operative Orthopadie und Traumatologie · 2015
    Article
  7. Review
  8. Article
  9. Article
  10. [Infected knee prostheses. Part 2: chronic late infections].Operative Orthopadie und Traumatologie · 2013
    Article
  11. [Knee joint infections].Der Unfallchirurg · 2013
    Article
  12. Article
  13. Article
  14. [Prevention of periprosthetic joint infections].Wiener medizinische Wochenschrift (1946) · 2012
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M MilitzBG Unfallklinik Murnau, Prof.-Küntscher-Strasse 8, Murnau, Germany. mmilitz@bgu-murnau.de
V Bühren
Berufsgenossenschaftliche Unfallklinik Murnau · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections occur in 0.5-5% of cases after implantation of an endoprosthesis and represent one of the most severe complications of artificial joint replacements. Approximately 300,000 primary implantations for hip and knee prostheses are carried out in Germany annually with a corresponding number of early and late infections. This means that approximately 4,000-6,000 cases are to be expected annually. Periprosthetic infections normally lead to a significant loss of function and quality of life for patients and the complex remediation is costly. Therefore, preventive measures, such as perioperative prophylaxis with antibiotics, maintaining highly sterile conditions during operations and an expedient selection of patients are of substantial importance. The basic principles of an adequate restoration include identification of the pathogen, local eradication of the infection mostly after removal of the prosthesis, pathogen-oriented systemic and local antibiotic therapy and finally re-implantation of the revision prosthesis under infection-free conditions. The standard procedure for revision surgery is a two-phase replacement with maintenance of an infection-free interval before renewal of the prosthesis. The use of single-phase or multi-phase strategies, as well as the selection of cemented or cement-free revision, varies between centers as a definitive evaluation is not yet available.The most important parameters for successful treatment of periprosthetic infections have been identified as the earliest possible diagnosis, radical surgical cleansing with an adequate antibiotic therapy and successful restoration has been reported in approximately 80% of cases. Because of the complex therapy regime, treatment in specialized centers is generally recommended especially under the aspect of a demanding patient monitoring.

Indexed as

Hip ProsthesisKnee ProsthesisAlgorithmsAnti-Bacterial AgentsCombined Modality TherapyDevice RemovalEarly DiagnosisEquipment Failure AnalysisHumansProsthesis-Related InfectionsReoperationAnti-Bacterial Agents

Identifiers

PMID20361365
OpenAlexW1565718898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.