Evidence map›Paper›PMID 20361326›Full record

ReviewApplied microbiology and biotechnology2010

Unraveling polyketide synthesis in members of the genus Aspergillus.

Yi-Ming Chiang, Berl R Oakley, Nancy P Keller, Clay C C Wang

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Whole Genome Identification and Biochemical Characteristics of theInternational journal of molecular sciences · 2024
    Article
  2. Journal of fungi (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Review
  5. Review
  6. Frontiers in microbiology · 2019
    Review
  7. Review
  8. A comprehensive catalogue of polyketide synthase gene clusters in lichenizing fungi.Journal of industrial microbiology & biotechnology · 2018
    Review
  9. Article
  10. Aflatoxins: Implications on Health.Indian journal of clinical biochemistry : IJCB · 2017
    Review
  11. Review
  12. Article
  13. Studies in mycology · 2016
    Article
  14. Article
  15. Article
  16. Synthetic biology of fungal natural products.Frontiers in microbiology · 2015
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi-Ming ChiangGraduate Institute of Pharmaceutical Science, Chia Nan University of Pharmacy and Science, Tainan, 71710, Taiwan, Republic of China.
Berl R Oakley
Nancy P Keller
Clay C C Wang

Funding

Molecular Genetic Mining of the Aspergillus Nidulans Secondary MetabolomeP01GM084077 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OAKLEY, BERL RAY · 2008 to 2012
$5.4M
THE MOLECULAR BIOLOGY OF ORGNELLAR TRANSLOCATIONR01GM031837 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OAKLEY, BERL RAY · 1985 to 2009
$2.9M
NIGMS NIH HHS P01 GM084077NIGMS NIH HHS P01GM084077NIGMS NIH HHS R01 GM031837NIGMS NIH HHS R01GM031837
6 · The paper itself

Abstract

Aspergillus species have the ability to produce a wide range of secondary metabolites including polyketides that are generated by multi-domain polyketide synthases (PKSs). Recent biochemical studies using dissected single or multiple domains from PKSs have provided deep insight into how these PKSs control the structural outcome. Moreover, the recent genome sequencing of several species has greatly facilitated the understanding of the biosynthetic pathways for these secondary metabolites. In this review, we will highlight the current knowledge regarding polyketide biosynthesis in Aspergillus based on the domain architecture of non-reducing, highly reducing, and partially reducing PKSs, and PKS-non-ribosomal peptide synthetases.

Indexed as

AspergillusBase SequenceBiosynthetic PathwaysHydrocarbonsLovastatinMycotoxinsOxidation-ReductionPigments, BiologicalPolyketide SynthasesProtein Structure, TertiaryHydrocarbonsLovastatinMycotoxinsPigments, BiologicalPolyketide Synthases

Identifiers

PMID20361326
PMCPMC3110678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.