Evidence map›Paper›PMID 20358282›Full record

ArticleJournal of fluorescence2010

Spectrometric studies on the sonodynamic damage of protein in the presence of levofloxacin.

Bin Liu, Jun Wang, Xin Wang, Bing-Mi Liu, Yu-Mei Kong, Dan Wang, Shu-Kun Xu

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Emerging Sonodynamic Therapy-Based Nanomedicines for Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Bin LiuDepartment of Chemistry, Northeastern University, Shenyang, 110004, People's Republic of China.
Jun Wang
Xin Wang
Bing-Mi Liu
Yu-Mei Kong
Dan Wang
Shu-Kun Xu
Liaoning University · CNNortheastern University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Taking bovine serum albumin (BSA) as typical molecules, the sonodynamic damage of protein in the presence of Levofloxacin (LVFX) and its mechanism were studied by fluorescence and UV-vis spectra. Various influencing factors such as ultrasonic irradiation time, pH value, ionic strength and solution temperature on the damage of BSA were also discussed. The results showed that ultrasound can enhance the damage of LVFX on BSA. The damage degree of BSA was aggravated with the increase of ultrasonic irradiation time, solution temperature and ionic strength, whereas decreased with the increase of solution pH value. Furthermore, the reactive oxygen species (ROS) in reaction system were studied by oxidation and extraction photometry. Experimental results showed that the amounts of superoxide anion radical (·O(2)(-)) and hydroxyl radical (·OH) were significantly more than that of singlet oxygen ((1)O(2)) in the presence of LVFX under ultrasonic irradiation.

Indexed as

LevofloxacinAnimalsCattleFluorescenceHydrogen-Ion ConcentrationHydroxyl RadicalOfloxacinOsmolar ConcentrationOxidation-ReductionReactive Oxygen SpeciesSerum Albumin, BovineSpectrometry, FluorescenceSpectrophotometry, UltravioletSpectrum AnalysisSuperoxidesTemperatureHydroxyl RadicalLevofloxacinOfloxacinReactive Oxygen SpeciesSerum Albumin, BovineSuperoxides

Identifiers

PMID20358282
OpenAlexW2042974736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.