ArticleInvestigative ophthalmology & visual science2010
Detection of cystoid macular edema with three-dimensional optical coherence tomography versus fluorescein angiography.
Article in Investigative ophthalmology & visual science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
- Evaluation of macular thickness changes after intracameral vancomycin in cataract surgery.International ophthalmology · 2015Trial
- Effect of fingolimod (FTY720) on cerebral blood flow, platelet function and macular thickness in healthy volunteers.British journal of clinical pharmacology · 2014Trial
- Evaluation of cystoid change phenotypes in ocular toxoplasmosis using optical coherence tomography.PloS one · 2014Trial
- Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema.Ophthalmology · 2013Trial
- Immune modulator therapy compared with vitrectomy for management of complicated intermediate uveitis: a prospective, randomized clinical study.Arquivos brasileiros de oftalmologiaTrial
- Incidence, Pathogenesis, Risk Factors, and Treatment of Cystoid Macula Oedema Following Cataract Surgery: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Review
- Multimodal Imaging in Unusual Alport Retinopathy.Cureus · 2024Article
- Are optical coherence tomography and fluorescein angiography comparable for detection of macular edema in Behçet uveitis?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Latent Diabetic Macular Edema in Chinese Diabetic Retinopathy Patients.Frontiers in medicine · 2021Article
- Postoperative cystoid macular oedema in a patient on fingolimod.BMJ case reports · 2015Article
- Retinal vessel diameter measurements by spectral domain optical coherence tomography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015Article
- An easy method to differentiate retinal arteries from veins by spectral domain optical coherence tomography: retrospective, observational case series.BMC ophthalmology · 2014Observational
- Safety and efficacy of oral fluorescein angiography in detecting macular edema in comparison with spectral-domain optical coherence tomography.Retina (Philadelphia, Pa.) · 2013Article
- The retinal disease screening study: prospective comparison of nonmydriatic fundus photography and optical coherence tomography for detection of retinal irregularities.Investigative ophthalmology & visual science · 2013Article
- Detection of clinical and subclinical retinal abnormalities in neurosarcoidosis with optical coherence tomography.Journal of neurology · 2012Article
- Spatial distribution of posterior pole choroidal thickness by spectral domain optical coherence tomography.Investigative ophthalmology & visual science · 2011Article
- Incidence of cystoid macular edema following routine cataract surgery using NSAIDs alone or with corticosteroids.Arquivos brasileiros de oftalmologiaObservational
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo compare the sensitivity and reproducibility of three-dimensional optical coherence tomography (3D-OCT) and fluorescein angiography (FA) for the detection of cystoid macular edema (CME).
methodsData were retrospectively collected from all patients who underwent digital FA and 512 × 128 horizontal raster 3D-OCT scans on the same day in a retina subspecialty clinic. Images were reviewed independently by four reading center graders and adjudicated as a group to render a single result for each eye and each imaging modality. The κ statistic was used to determine the level of agreement between graders for each modality. The sensitivity of each imaging modality for CME detection was calculated by using the presence of CME on either modality as the ground truth; subgroup analysis was performed according to disease diagnosis and lens status.
resultsFour hundred thirteen eyes of 207 patients were included in the analysis. Intergrader agreement was higher for 3D-OCT than for FA both before (κ(OCT) = 0.61, κ(FA) = 0.43) and after adjudication (κ(OCT) = 0.74, κ(FA) = 0.58).The sensitivity for detection of definite CME was higher for 3D-OCT (95%, 144/151 cases) than for FA (44%, 67/151 cases). Definite FA (+) 3D-OCT (-) CME was identified in 1 eye (0.2%), whereas definite FA (-) 3D-OCT (+) CME was identified in 40 eyes (10%). No significant associations between CME detection and lens examination or disease diagnosis were observed.
conclusionsIn this study, 3D-OCT was more sensitive and had better intergrader agreement than did FA for the detection of CME.
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