ArticleGenome research2010
Pronounced inter- and intrachromosomal variation in linkage disequilibrium across the zebra finch genome.
Article in Genome research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Molecular Evolution of a Sex-Linked Inversion Polymorphism in Zebra Finches.Genome biology and evolution · 2026Article
- Biochemical and Genomic Underpinnings of Carotenoid Colour Variation Across a Hybrid Zone Between South Asian Flameback Woodpeckers.Molecular ecology · 2025Article
- Fine-Scale Map Reveals Highly Variable Recombination Rates Associated with Genomic Features in the Eurasian Blackcap.Genome biology and evolution · 2024Article
- The genome of a globally invasive passerine, the common myna, Acridotheres tristis.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024Article
- Variation in DNA Methylation in Avian Nestlings Is Largely Determined by Genetic Effects.Molecular biology and evolution · 2023Article
- A chromosome-level reference genome and pangenome for barn swallow population genomics.Cell reports · 2023Article
- MLH1 focus mapping in the guinea fowl (Numida meleagris) give insights into the crossover landscapes in birds.PloS one · 2020Article
- Migration-Selection Balance Drives Genetic Differentiation in Genes Associated with High-Altitude Function in the Speckled Teal (Anas flavirostris) in the Andes.Genome biology and evolution · 2018Article
- Low recombination rates in sexual species and sex-asex transitions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Variation in recombination frequency and distribution across eukaryotes: patterns and processes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Pedigree-based inbreeding coefficient explains more variation in fitness than heterozygosity at 160 microsatellites in a wild bird population.Proceedings. Biological sciences · 2017Article
- Linkage mapping of a polymorphic plumage locus associated with intermorph incompatibility in the Gouldian finch (Erythrura gouldiae).Heredity · 2016Article
- Temporal dynamics of linkage disequilibrium in two populations of bighorn sheep.Ecology and evolution · 2015Article
- Highly variable recombinational landscape modulates efficacy of natural selection in birds.Genome biology and evolution · 2014Article
- Article
- Genetic mapping of the major histocompatibility complex in the zebra finch (Taeniopygia guttata).Immunogenetics · 2011Article
- Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization.BMC research notes · 2011Article
- The singing genome.Heredity · 2011Article
- Linkage disequilibrium and past effective population size in native Tunisian cattle.Genetics and molecular biologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The extent of nonrandom association of alleles at two or more loci, termed linkage disequilibrium (LD), can reveal much about population demography, selection, and recombination rate, and is a key consideration when designing association mapping studies. Here, we describe a genome-wide analysis of LD in the zebra finch (Taeniopygia guttata) using 838 single nucleotide polymorphisms and present LD maps for all assembled chromosomes. We found that LD declined with physical distance approximately five times faster on the microchromosomes compared to macrochromosomes. The distribution of LD across individual macrochromosomes also varied in a distinct pattern. In the center of the macrochromosomes there were large blocks of markers, sometimes spanning tens of mega bases, in strong LD whereas on the ends of macrochromosomes LD declined more rapidly. Regions of high LD were not simply the result of suppressed recombination around the centromere and this pattern has not been observed previously in other taxa. We also found evidence that this pattern of LD has remained stable across many generations. The variability in LD between and within chromosomes has important implications for genome wide association studies in birds and for our understanding of the distribution of recombination events and the processes that govern them.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.