ArticleGenome research2010
Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution.
Article in Genome research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
92 citing papers in PubMed, 158 citations in OpenAlex.
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- Bridging methodological gaps in avian cytogenetics: comprehensive and optimized protocols for chromosomal preparation in birds.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026Article
- Multidirectional Chromosomal Painting in the Harpy Eagle (Animals : an open access journal from MDPI · 2026Article
- The genetic basis of mimicry in the snowy bumble bee (Bombus niveatus) in Anatolia with insights from a color polymorphic gynandromorph.PLoS genetics · 2026Article
- CNAttention: an attention-based deep multiple-instance method for uncovering copy number aberration signatures across cancers.Briefings in bioinformatics · 2026Article
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- Lepidopteran Genomes Have Denser Transposable Elements in Smaller Chromosomes, Likely Driven by Non-allelic Homologous Recombination.Genome biology and evolution · 2025Article
- The adaptive value of recombination in resolving intralocus sexual conflict by gene duplication.Proceedings. Biological sciences · 2025Article
- Omics Biology in Diagnosis of Diseases: Towards Empowering Genomic Medicine from an Evolutionary Perspective.Life (Basel, Switzerland) · 2024Article
- A region of suppressed recombination misleads neoavian phylogenomics.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Identification of the genetic characteristics of copy number variations in experimental specific pathogen-free ducks using whole-genome resequencing.BMC genomics · 2024Article
- A high-quality genome assembly highlights the evolutionary history of the great bustard (Otis tarda, Otidiformes).Communications biology · 2023Article
- Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity.Nature communications · 2023Article
- Comprehensive Analysis of Copy Number Variations on Glycoside Hydrolase 45 Genes among DifferentInternational journal of molecular sciences · 2022Article
- Linked-Read Sequencing of Eight Falcons Reveals a Unique Genomic Architecture in Flux.Genome biology and evolution · 2022Article
- Intra-specific copy number variation of MHC class II genes in the Siamese fighting fish.Immunogenetics · 2022Article
- Cytogenetic Evidence Clarifies the Phylogeny of the Family Rhynchocyclidae (Aves: Passeriformes).Cells · 2021Article
- Why Do Some Vertebrates Have Microchromosomes?Cells · 2021Review
- Karyotype Evolution and Genomic Organization of Repetitive DNAs in the Saffron Finch,Animals : an open access journal from MDPI · 2021Article
32 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Chromosomal rearrangements and copy number variants (CNVs) play key roles in genome evolution and genetic disease; however, the molecular mechanisms underlying these types of structural genomic variation are not fully understood. The availability of complete genome sequences for two bird species, the chicken and the zebra finch, provides, for the first time, an ideal opportunity to analyze the relationship between structural genomic variation (chromosomal and CNV) and recombination on a genome-wide level. The aims of this study were therefore threefold: (1) to combine bioinformatics, physical mapping to produce comprehensive comparative maps of the genomes of chicken and zebra finch. In so doing, this allowed the identification of evolutionary chromosomal rearrangements distinguishing them. The previously reported interchromosomal conservation of synteny was confirmed, but a larger than expected number of intrachromosomal rearrangements were reported; (2) to hybridize zebra finch genomic DNA to a chicken tiling path microarray and identify CNVs in the zebra finch genome relative to chicken; 32 interspecific CNVs were identified; and (3) to test the hypothesis that there is an association between CNV, chromosomal rearrangements, and recombination by correlating data from (1) and (2) with recombination rate data from a high-resolution genetic linkage map of the zebra finch. We found a highly significant association of both chromosomal rearrangements and CNVs with elevated recombination rates. The results thus provide support for the notion of recombination-based processes playing a major role in avian genome evolution.
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