ReviewAmerican journal of physiology. Regulatory, integrative and comparative physiology2010
Physical (in)activity-dependent alterations at the rostral ventrolateral medulla: influence on sympathetic nervous system regulation.
Review in American journal of physiology. Regulatory, integrative and comparative physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 58 citations in OpenAlex.
- Effects of aerobic training on cardiopulmonary fitness in patients with long COVID-19: a randomized controlled trial.Trials · 2024Trial
- The development but not the maintenance of phrenic and sympathetic long-term facilitation after acute intermittent hypoxia requires nucleus tractus solitarii HExperimental neurology · 2025Article
- Sulfur Dioxide Alleviates Organ Damage and Inflammatory Response in Cecal Ligation and Puncture-Induced Sepsis Rat.Molecular biotechnology · 2025Article
- Do the associations of daily steps with mortality and incident cardiovascular disease differ by sedentary time levels? A device-based cohort study.British journal of sports medicine · 2024Article
- Sex-dependent development of enhanced sympathoexcitation in sedentary versus physically active rats.The Journal of physiology · 2021Article
- Neuroplasticity in N-methyl-d-aspartic acid receptor signaling in subregions of the rat rostral ventrolateral medulla following sedentary versus physically active conditions.The Journal of comparative neurology · 2021Article
- Physical activity, sleep and neuropsychiatric symptom severity in children with tourette syndrome.European child & adolescent psychiatry · 2021Article
- Sedentary Conditions Promote Subregionally Specific Changes in Brain-Derived Neurotrophic Factor in the Rostral Ventrolateral Medulla.Frontiers in physiology · 2021Article
- Subregional differences in GABAThe Journal of comparative neurology · 2020Article
- Thermoregulation in Hypertensive Rats during Exercise: Effects of Physical Training.Arquivos brasileiros de cardiologia · 2019Article
- Objectively Measured Sitting and Standing in Workers: Cross-Sectional Relationship with Autonomic Cardiac Modulation.International journal of environmental research and public health · 2019Article
- Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors.Nature reviews. Cardiology · 2018Review
- Effects of Exercise on Vascular Function, Structure, and Health in Humans.Cold Spring Harbor perspectives in medicine · 2018Review
- Development of manganese-enhanced magnetic resonance imaging of the rostral ventrolateral medulla of conscious rats: Importance of normalization and comparison with other regions of interest.NMR in biomedicine · 2018Article
- Alterations in autonomic cerebrovascular control after spinal cord injury.Autonomic neuroscience : basic & clinical · 2018Review
- Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli.Physiological reviews · 2017Review
- Exercise training attenuates renovascular hypertension partly via RAS- ROS- glutamate pathway in the hypothalamic paraventricular nucleus.Scientific reports · 2016Article
- Article
- Altered Differential Control of Sympathetic Outflow Following Sedentary Conditions: Role of Subregional Neuroplasticity in the RVLM.Frontiers in physiology · 2016Article
- Prolonged Sitting is Associated with Attenuated Heart Rate Variability during Sleep in Blue-Collar Workers.International journal of environmental research and public health · 2015Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
A sedentary lifestyle is a major risk factor for cardiovascular disease, and rates of inactivity and cardiovascular disease are highly prevalent in our society. Cardiovascular disease is often associated with overactivity of the sympathetic nervous system, which has both direct and indirect effects on multiple organ systems. Although it has been known for some time that exercise positively affects the brain in terms of memory and cognition, only recently have changes in how the brain regulates the cardiovascular system been examined in terms of physical activity and inactivity. This brief review will discuss the evidence for physical activity-dependent neuroplasticity related to control of sympathetic outflow. It will focus particularly on recent studies from our laboratory and others that have examined changes that occur in the rostral ventrolateral medulla (RVLM), considered one of the primary brain regions involved in the regulation and generation of sympathetic nervous system activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.