ArticleProceedings. Biological sciences2010
Nutrient provisioning facilitates homeostasis between tsetse fly (Diptera: Glossinidae) symbionts.
Article in Proceedings. Biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed, 100 citations in OpenAlex.
- Friends or foes: Unraveling the tsetse fly-Spiroplasma symbiosis.PLoS neglected tropical diseases · 2026Review
- Laboratory evolution drives continued genome degradation in the facultative tsetse symbiont Sodalis glossinidius.PLoS neglected tropical diseases · 2026Article
- mir-31 mediated control of bacteriome size in tsetse flies.Current research in insect science · 2025Article
- How do host age and nutrition affect density regulation of obligate versus facultative bacterial symbionts? Insights from the tsetse fly.ISME communications · 2025Article
- Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes.Parasites & vectors · 2024Article
- Draft genome sequence ofMicrobiology resource announcements · 2024Article
- Review
- Prevalence of Spiroplasma and interaction with wild Glossina tachinoides microbiota.Parasite (Paris, France) · 2023Article
- Endosymbiont-containing germarium transcriptional survey in a cereal weevil depicts downregulation of immune effectors at the onset of sexual maturity.Frontiers in physiology · 2023Article
- Article
- Marine vampires: Persistent, internal associations between bacteria and blood-feeding marine annelids and crustaceans.Frontiers in microbiology · 2022Article
- The Tsetse Metabolic Gambit: Living on Blood by Relying on Symbionts Demands Synchronization.Frontiers in microbiology · 2022Review
- Article
- Insect-host control of obligate, intracellular symbiont density.Proceedings. Biological sciences · 2021Article
- Infection with endosymbiotic Spiroplasma disrupts tsetse (Glossina fuscipes fuscipes) metabolic and reproductive homeostasis.PLoS pathogens · 2021Article
- The holobiont transcriptome of teneral tsetse fly species of varying vector competence.BMC genomics · 2021Article
- Microbial Response to Fungal Infection in a Fungus-Growing Termite,Frontiers in microbiology · 2021Article
- Immunometabolism in Arthropod Vectors: Redefining Interspecies Relationships.Trends in parasitology · 2020Review
- Biotin provisioning by horizontally transferred genes from bacteria confers animal fitness benefits.The ISME journal · 2020Article
- Functional Variation in Dipteran Gut Bacterial Communities in Relation to Their Diet, Life Cycle Stage and Habitat.Insects · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Host-associated microbial interactions may involve genome complementation, driving-enhanced communal efficiency and stability. The tsetse fly (Diptera: Glossinidae), the obligate vector of African trypanosomes (Trypanosoma brucei subspp.), harbours two enteric Gammaproteobacteria symbionts: Wigglesworthia glossinidia and Sodalis glossinidius. Host coevolution has streamlined the Wigglesworthia genome to complement the exclusively sanguivorous tsetse lifestyle. Comparative genomics reveal that the Sodalis genome contains the majority of Wigglesworthia genes. This significant genomic overlap calls into question why tsetse maintains the coresidence of both symbionts and, furthermore, how symbiont homeostasis is maintained. One of the few distinctions between the Wigglesworthia and Sodalis genomes lies in thiamine biosynthesis. While Wigglesworthia can synthesize thiamine, Sodalis lacks this capability but retains a thiamine ABC transporter (tbpAthiPQ) believed to salvage thiamine. This genetic complementation may represent the early convergence of metabolic pathways that may act to retain Wigglesworthia and evade species antagonism. We show that thiamine monophosphate, the specific thiamine derivative putatively synthesized by Wigglesworthia, impacts Sodalis thiamine transporter expression, proliferation and intracellular localization. A greater understanding of tsetse symbiont interactions may generate alternative control strategies for this significant medical and agricultural pest, while also providing insight into the evolution of microbial associations within hosts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.