Trial reportEuropean journal of applied physiology2010
Influence of cerebral and muscle oxygenation on repeated-sprint ability.
Trial report in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Cerebral and muscle tissue oxygenation during exercise in healthy adults: A systematic review.Journal of sport and health science · 2024Pooled it
- Experiment protocols for brain-body imaging of locomotion: A systematic review.Frontiers in neuroscience · 2023Pooled it
- Trial
- Dose-response effects of caffeine during repeated cycling sprints in normobaric hypoxia to exhaustion.European journal of applied physiology · 2025Trial
- Acute Effects of Brief Mindfulness Intervention Coupled with Carbohydrate Ingestion to Re-Energize Soccer Players: A Randomized Crossover Trial.International journal of environmental research and public health · 2020Trial
- Enhancement of Exercise Performance by 48 Hours, and 15-Day Supplementation with Mangiferin and Luteolin in Men.Nutrients · 2019Trial
- Muscle oxygenation maintained during repeated-sprints despite inspiratory muscle loading.PloS one · 2019Trial
- Exercise-related sensations contribute to decrease power during repeated cycle sprints with limited influence on neural drive.European journal of applied physiology · 2017Trial
- Repeated sprint training in normobaric hypoxia.British journal of sports medicine · 2013Trial
- Interaction of central and peripheral factors during repeated sprints at different levels of arterial O2 saturation.PloS one · 2013Trial
- Effect of endurance training on performance and muscle reoxygenation rate during repeated-sprint running.European journal of applied physiology · 2011Trial
- Integrating mechanical, physiological, and muscle oxygenation responses during field-based tethered repeated-sprint exercise in male professional soccer players.Physiological reports · 2026Article
- Advances in fully integrated wearable near-infrared spectroscopy: hardware innovations and biomedical applications.JPhys photonics · 2026Review
- Acute physiological responses during repeated sprint training with maximum end-expiratory breath-holds.European journal of applied physiology · 2026Article
- A theoretical framework for predicting altitude effects on physical employment standard evaluation performance.Frontiers in physiology · 2026Article
- Effects of caffeinated chewing gum on prolonged repeated-sprint performance in normobaric hypoxia.Frontiers in nutrition · 2026Article
- Muscle deoxygenation responses are similar between repeated sprints in hypoxia performed with uni- versus bi-lateral knee extensions but reduced compared to cycling.European journal of sport science · 2025Article
- Time-continuous analysis of muscle and cerebral oxygenation during repeated treadmill sprints under heat stress: a statistical parametric mapping study.European journal of applied physiology · 2025Article
- Repeated-sprint training with low lung volume voluntary hypoventilation performed continuously throughout each set in healthy females.Frontiers in physiology · 2025Article
- Cardiorespiratory and muscle oxygenation responses to voluntary hypoventilation at low lung volume in upper body repeated sprints.European journal of applied physiology · 2024Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study examined the influence of cerebral (prefrontal cortex) and muscle (vastus lateralis) oxygenation on the ability to perform repeated, cycling sprints. Thirteen team-sport athletes performed ten, 10-s sprints (with 30 s of rest) under normoxic (F(I)O(2) 0.21) and acute hypoxic (F(I)O(2) 0.13) conditions in a randomised, single-blind fashion and crossover design. Mechanical work was calculated and arterial O(2) saturation (S(p)O(2)) was estimated via pulse oximetry for every sprint. Cerebral and muscle oxy-(O(2)Hb), deoxy-(HHb), and total haemoglobin (THb) were monitored continuously by near-infrared spectroscopy. Compared with normoxia, hypoxia induced larger decrements in S(p)O(2) and work (11.6 and 7.6%, respectively; P < 0.05). In the muscle, we observed a fairly constant level of deoxygenation across sprints, with no effect of the condition. In normoxia, regional cerebral oxygenation increased during the first two sprints and slightly fluctuated thereafter. In contrast, this initial cerebral hyper-oxygenation was attenuated in hypoxia. Changes in [O(2)Hb] and [HHb] occurred earlier and were larger in hypoxia compared with normoxia (P < 0.05), while regional blood volume (Delta[THb]) remained unaffected by the condition. Changes in cerebral [HHb] and mechanical work were strongly correlated in normoxia and hypoxia (R(2) = 0.81 and R(2) = 0.85, respectively; P < 0.05), although the slope of this relationship differed (normoxia, -351.3 +/- 183.3 vs. hypoxia, -442.4 +/- 227.2; P < 0.05). The results of this NIRS study show that O(2) availability influences prefrontal cortex, but not muscle, oxygenation during repeated, short sprints. By using a hypoxia paradigm, the study suggests that cerebral oxygenation contributes to the impairment of repeated-sprint ability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.