Evidence map›Paper›PMID 20354444›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2010

Results of the NIMH collaborative HIV/sexually transmitted disease prevention trial of a community popular opinion leader intervention.

NIMH Collaborative HIV/STD Prevention Trial Group

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
24.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Pooled it
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  10. Assessing outcomes of a stigma-reduction intervention with venue-based analysis.Social psychiatry and psychiatric epidemiology · 2014
    Trial
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  12. Trial
  13. Popular Opinion Leader intervention for HIV stigma reduction in health care settings.AIDS education and prevention : official publication of the International Society for AIDS Education · 2013
    Trial
  14. Trial
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

NIMH Collaborative HIV/STD Prevention Trial Group
National Institute of Mental Health · US

Funding

International Center for Excellence in Research (ICER) in Uganda: Impact of ARVsZIAAI001040 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REYNOLDS, STEVEN · 2009 to 2025
$23.5M
International Studies of the Acquired Immune Deficiency Syndrome (AIDS)ZIAAI000361 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REDD, ANDREW · 2009 to 2025
$15.8M
NIMH COLLABORATIVE HIV/STD PREVENTION TRIALU10MH061537 · NIMH · RESEARCH TRIANGLE INSTITUTE · PI HARTWELL, TYLER D · 1999 to 2009
$15.2M
NIMH COLLABORATIVE HIV/STD PREVENTION TRIALU10MH061536 · NIMH · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI COATES, THOMAS J. · 1999 to 2006
$10.7M
ZIMBABWE--COMMUNITY INTERVENTION TO REDUCE HIV/STD RISKU10MH061544 · NIMH · BATTELLE CENTERS/PUB HLTH RES &EVALUATN · PI KASPRZYK, DANUTA · 2000 to 2006
$10.3M
NIMH Collaborative HIV/STD Prevention Trial -- IndiaU10MH061543 · NIMH · JOHNS HOPKINS UNIVERSITY · PI CELENTANO, DAVID D. · 1999 to 2006
$10.1M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
OPINION LEADER HIV INTERVENTION AMONG MIGRANT CHINESEU10MH061513 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM, MARY JANE · 1999 to 2007
$8.4M
NIMH Collaborative HIV/STD Prevention Trial (Russia)U10MH061499 · NIMH · MEDICAL COLLEGE OF WISCONSIN · PI SOMLAI, ANTON M · 1999 to 2006
$7.7M
Immunopathogenesis Of Chlamydia trachomatis InfectionZIAAI000358 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI QUINN, THOMAS · 2009 to 2022
$7.0M
NICHD NIH HHS R24 HD050924NIMH NIH HHS U10 MH061499NIMH NIH HHS U10MH061499NIMH NIH HHS U10 MH061513NIMH NIH HHS U10MH061513NIMH NIH HHS U10 MH061536NIMH NIH HHS U10MH061536NIMH NIH HHS U10 MH061537NIMH NIH HHS U10MH061537NIMH NIH HHS U10 MH061543NIMH NIH HHS U10MH061543NIMH NIH HHS U10 MH061544NIMH NIH HHS U10MH061544
6 · The paper itself

Abstract

objectiveTo determine whether community populations in community popular opinion leader intervention venues showed greater reductions in sexual risk practices and lower HIV/sexually transmitted disease (STD) incidence than those in comparison venues.

methodsA 5-country group-randomized trial, conducted from 2002 to 2007, enrolled cohorts from 20 to 40 venues in each country. Venues, matched within country on sexual risk and other factors, were randomly assigned within matched pairs to the community popular opinion leader intervention or an AIDS education comparison. All participants had access to condoms and were assessed with repeated in-depth sexual behavior interviews, STD/HIV testing and treatment, and HIV/STD risk-reduction counseling. Sexual behavior change and HIV/STD incidence were measured over 2 years.

resultsBoth intervention and comparison conditions showed declines of approximately 33% in risk behavior prevalence and had comparable diseases incidence within and across countries.

conclusionsThe community-level intervention did not produce greater behavioral risk and disease incidence reduction than the comparison condition, perhaps due to the intensive prevention services received by all participants during the assessment. Repeated detailed self-review of risk behavior practices coupled with HIV/STD testing, treatment, HIV risk-reduction counseling, and condom access can themselves substantially change behavior and disease acquisition.

Indexed as

AdultChinaCommunity Health ServicesFemaleHIV InfectionsHumansIndiaInterviews as TopicLeadershipMalePatient Education as TopicPeruPrevalenceRussiaSexual BehaviorSexually Transmitted Diseases

Identifiers

PMID20354444
PMCPMC2904551
OpenAlexW2795879260

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.