ReviewCancer prevention research (Philadelphia, Pa.)2010
NF-kappaB fans the flames of lung carcinogenesis.
Review in Cancer prevention research (Philadelphia, Pa.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Critical and distinct roles of cell type-specific NF-κB2 in lung cancer.JCI insight · 2024Article
- Implications of xenobiotic-response element(s) and aryl hydrocarbon receptor in health and diseases.Human cell · 2023Review
- DNAJC12 promotes lung cancer growth by regulating the activation of β‑catenin.International journal of molecular medicine · 2021Article
- Comparison of COVID-19 and Lung CancerFrontiers in oncology · 2021Review
- Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance.Nature communications · 2019Article
- NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.Oncogene · 2016Article
- Aryl hydrocarbon receptor and lung cancer.Anticancer research · 2013Review
- Identification of oxidative stress related proteins as biomarkers for lung cancer and chronic obstructive pulmonary disease in bronchoalveolar lavage.International journal of molecular sciences · 2013Article
- KRAS mutation and NF-κB activation indicates tolerance of chemotherapy and poor prognosis in colorectal cancer.Digestive diseases and sciences · 2012Article
- Opposing effects of bortezomib-induced nuclear factor-κB inhibition on chemical lung carcinogenesis.Carcinogenesis · 2012Article
- NF-kappaB in lung tumorigenesis.Cancers · 2011Article
- NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target.Frontiers in bioscience (Landmark edition) · 2011Review
Corrections and comments
- Comment on
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-kappaB and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating protumorigenic roles of NF-kappaB activation in lung cancer pathogenesis. Our growing understanding of the tumor-promoting NF-kappaB downstream effector pathways could lead to the development of novel approaches for lung cancer therapy and chemoprevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.