Evidence map›Paper›PMID 20353873›Full record

ArticleVirology2010

Emergence of a novel and highly divergent HTLV-3 in a primate hunter in Cameroon.

HaoQiang Zheng, Nathan D Wolfe, David M Sintasath, Ubald Tamoufe, Matthew Lebreton, Cyrille F Djoko, Joseph Le Doux Diffo, Brian L Pike, Walid Heneine, William M Switzer

Abstract read
In one paragraph

Article in Virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

HaoQiang ZhengLaboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Nathan D Wolfe
David M Sintasath
Ubald Tamoufe
Matthew Lebreton
Cyrille F Djoko
Joseph Le Doux Diffo
Brian L Pike
Walid Heneine
William M Switzer
Global Viral · USCenters for Disease Control and Prevention · USJohns Hopkins University · US

Funding

TUBERCULOSIS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW000010 · FIC · JOHNS HOPKINS UNIVERSITY · PI BEYRER, CHRISTOPHER C. · 1988 to 2012
$19.8M
NIH Director's Pioneer Award (RMI)DP1OD000370 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOLFE, NATHAN D · 2005 to 2009
$3.4M
THE EMERGENCE OF HIV GENETIC DIVERSITY IN CAMEROONK01TW000003 · FIC · JOHNS HOPKINS UNIVERSITY · PI WOLFE, NATHAN D · 1999 to 2005
$634k
FIC NIH HHS 2 D 43TW000010-17FIC NIH HHS 5 K01 TW000003-05FIC NIH HHS D43 TW000010FIC NIH HHS K01 TW000003NIH HHS DP1 OD000370NIH HHS DP1-OD000370
6 · The paper itself

Abstract

The recent discovery of human T-lymphotropic virus type 3 (HTLV-3) in Cameroon highlights the importance of expanded surveillance to better understand the prevalence and public health impact of this new retrovirus. HTLV diversity was investigated in 408 persons in rural Cameroon who reported simian exposures. Plasma from 29 persons (7.2%) had reactive serology. HTLV tax sequences were detected in 3 persons. Phylogenetic analysis confirmed HTLV-1 infection in two individuals and HTLV-3 infection in a third person (Cam2013AB). The complete proviral genome from Cam2013AB shared 98% identity and clustered tightly in distinct lineage with simian T-lymphotropic virus type 3 (STLV-3) subtype D recently identified in two guenon monkeys near this person's village. These results document a fourth HTLV-3 infection with a new and highly divergent strain we designate HTLV-3 (Cam2013AB) subtype D demonstrating the existence of a broad HTLV-3 diversity likely originating from multiple zoonotic transmissions of divergent STLV-3.

Indexed as

Genetic VariationAdolescentAdultAnimalsCameroonCluster AnalysisDeltaretrovirus InfectionsFemaleGene Products, taxGenome, ViralHaplorhiniHumansHuman T-lymphotropic virus 3MaleMiddle AgedMolecular Sequence DataGene Products, tax

Identifiers

PMID20353873
PMCPMC2862145
OpenAlexW2094241145

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.