Evidence map›Paper›PMID 20353302›Full record

ReviewFuture microbiology2010

Tissue tropisms in group A streptococcal infections.

Debra E Bessen, Sergio Lizano

Open access · greenAbstract readReview
In one paragraph

Review in Future microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
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  6. A worldwide population ofThe Lancet regional health. Western Pacific · 2024
    Article
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  20. Canada-Wide Epidemic ofOpen forum infectious diseases · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Debra E BessenDepartment of Microbiology & Immunology, New York Medical College, Valhalla, NY 10573, USA. debra_bessen@nymc.edu
Sergio Lizano
IDEXX Laboratories (United States) · USNew York Medical College · US

Funding

Population genomics of Streptococcus pyogenesR01AI065572 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2005 to 2009
$1.8M
Tissue-Specific Infection by Group A StreptococciR01AI053826 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2003 to 2007
$1.3M
EVOLUTION OF GROUP A STREPTOCOCCIR01GM060793 · NIGMS · YALE UNIVERSITY · PI BESSEN, DEBRA E · 2000 to 2004
$1.1M
Tissue-Specific Infection by Group A StreptococciR56AI053826 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2008 to 2009
$808k
NIAID NIH HHS AI-053826NIAID NIH HHS AI-065572NIAID NIH HHS R01 AI053826NIAID NIH HHS R01 AI065572NIAID NIH HHS R56 AI053826NIGMS NIH HHS GM-60793NIGMS NIH HHS R01 GM060793
6 · The paper itself

Abstract

Group A Streptococcus (GAS) is a human-specific pathogen that is highly prevalent throughout the world. The vast majority of GAS infections lead to a mild disease involving the epithelial surfaces of either the throat or skin. The concept of distinct sets of 'throat' and 'skin' strains of GAS has long been conceived. From an ecological standpoint, the epithelium of the throat and skin are important because it is where the organism is most successful in reproducing and transmitting to new hosts. This article examines key features of the epidemiology, population biology and molecular pathogenesis that underlie the tissue site preferences for infection exhibited by GAS, with an emphasis on work from our laboratory on skin tropisms. Recombinational replacement with orthologous gene forms, following interspecies transfer, appears to be an important genetic step leading up to the exploitation of new niches by GAS.

Indexed as

Bacterial ProteinsBacterial Typing TechniquesEpitheliumGenotypeHumansPharynxSkinStreptococcal InfectionsStreptococcus pyogenesVirulence FactorsBacterial ProteinsVirulence Factors

Identifiers

PMID20353302
PMCPMC2901552
OpenAlexW2160459795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.