ReviewClinical reviews in allergy & immunology2011
Chemokines and their receptors in the allergic airway inflammatory process.
Review in Clinical reviews in allergy & immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway.PLoS pathogens · 2025Article
- Expression of CCR8 and CCX-CKR on Basophils in Chronic Urticaria Is Amplified by IgE-Mediated Activation.Biomedicines · 2023Article
- Pharmacological OGG1 inhibition decreases murine allergic airway inflammation.Frontiers in pharmacology · 2022Article
- β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells.American journal of respiratory cell and molecular biology · 2018Article
- T-Helper Type 2 Cells Direct Antigen-Induced Eosinophilic Skin Inflammation in Mice.Allergy, asthma & immunology research · 2018Article
- Kinetic mRNA Profiling in a Rat Model of Left-Ventricular Hypertrophy Reveals Early Expression of Chemokines and Their Receptors.PloS one · 2016Article
- Unmet needs in respiratory diseases : "You can't know where you are going until you know where you have been"--Anonymous.Clinical reviews in allergy & immunology · 2013Review
- Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation.Molecular immunology · 2013Article
- Aspirin-intolerant asthma: a comprehensive review of biomarkers and pathophysiology.Clinical reviews in allergy & immunology · 2013Review
- Xiaoqinglong granules as add-on therapy for asthma: latent class analysis of symptom predictors of response.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Novel challenges for the allergist.Clinical reviews in allergy & immunology · 2011Article
- Reactive oxygen species mediate inflammatory cytokine release and EGFR-dependent mucin secretion in airway epithelial cells exposed to Pseudomonas pyocyanin.Mucosal immunology · 2011Article
- Porphyromonas gingivalis-dendritic cell interactions: consequences for coronary artery disease.Journal of oral microbiology · 2010Article
- A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of the allergic airway disease conveys several cell types, such as T-cells, eosinophils, mast cells, and dendritic cells, which act in a special and temporal synchronization. Cellular mobilization and its complex interactions are coordinated by a broad range of bioactive mediators known as chemokines. These molecules are an increasing family of small proteins with common structural motifs and play an important role in the recruitment and cell activation of both leukocytes and resident cells at the allergic inflammatory site via their receptors. Trafficking and recruitment of cell populations with specific chemokines receptors assure the presence of reactive allergen-specific T-cells in the lung, and therefore the establishment of an allergic inflammatory process. Different approaches directed against chemokines receptors have been developed during the last decades with promising therapeutic results in the treatment of asthma. In this review we explore the role of the chemokines and chemokine receptors in allergy and asthma and discuss their potential as targets for therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.