Evidence map›Paper›PMID 20352428›Full record

ReviewCancer immunology, immunotherapy : CII2010

Th17 cells: positive or negative role in tumor?

Yuqiang Ji, Wanggang Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer immunology, immunotherapy : CII, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
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  5. Review
  6. Review
  7. Function and Application of Flavonoids in the Breast Cancer.International journal of molecular sciences · 2022
    Review
  8. Interleukin 25 (IL-25) expression in cholangiocarcinoma.Molecular and clinical oncology · 2020
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Evaluation of mRNA expression levels of IL-17A and IL-10 cytokines in cervical cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  18. Article
  19. Article
  20. Staphylococcal enterotoxin B/texosomes as a candidate for breast cancer immunotherapy.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuqiang JiDepartment of Clinical Hematology, Second Hospital of Xi'an Jiaotong University, Xi'an, China.
Wanggang Zhang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Th17 cells have been recently identified as a distinct Th cell lineage and found in an experimental animal model of cancer and in human cancers, but whether these cells promote tumor growth or regulate antitumor responses remains controversial. This review provides a summary of the current literature regarding interleukin (IL)-17/IL-23 and Th17 cells in cancer and discusses their potential roles in cancer development. Finally, we note several issues in this research area that must be resolved before the design of novel therapeutic approaches specifically targeting Th17 cells in cancer become feasible.

Indexed as

AnimalsHumansInterleukin-17Interleukin-23Models, ImmunologicalNeoplasmsTh1 CellsTh2 CellsT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryInterleukin-17Interleukin-23

Identifiers

PMID20352428
PMCPMC11031007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.