Trial reportAIDS and behavior2010
Vaginal practices and associations with barrier methods and gel use among Sub-Saharan African women enrolled in an HIV prevention trial.
Trial report in AIDS and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis.PLoS medicine · 2011Pooled it
- Negative rumours about a vaginal ring for HIV-1 prevention in sub-Saharan Africa.Culture, health & sexuality · 2019Trial
- Impact of targeted counseling on reported vaginal hygiene practices and bacterial vaginosis: the HIV Prevention Trials Network 035 study.International journal of STD & AIDS · 2017Trial
- Effect of treatment assignment on intravaginal cleansing in a randomized study of the diaphragm with candidate microbicide.Journal of women's health (2002) · 2011Trial
- Vaginal practices among women at risk for HIV acquisition in Soweto, South Africa.Southern African journal of HIV medicine · 2019Article
- 'You'll always stay right': understanding vaginal products and the motivations for use among adolescent and young women in rural KZN.Culture, health & sexuality · 2019Article
- The implications of post-coital intravaginal cleansing for the introduction of vaginal microbicides in South Africa.AIDS and behavior · 2014Article
- Understanding motives for intravaginal practices amongst Tanzanian and Ugandan women at high risk of HIV infection: the embodiment of social and cultural norms and well-being.Social science & medicine (1982) · 2014Article
- Chlamydia and Gonorrhea Infections in HIV-positive Women in Urban Lusaka, Zambia.Journal of global infectious diseases · 2012Article
- Cultural differences in acceptability of a vaginal microbicide: a comparison between potential users from Nashville, Tennessee, USA, and Kafue and Mumbwa, Zambia.HIV/AIDS (Auckland, N.Z.) · 2012Article
- Vaginal practices of HIV-negative Zimbabwean women.Infectious diseases in obstetrics and gynecology · 2010Article
- An intervention to decrease intravaginal practices in hiv-infected women in Zambia: a pilot study.The Journal of the Association of Nurses in AIDS Care : JANACArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vaginal practices may interfere with the use and/or the effectiveness of female-initiated prevention methods. We investigated whether vaginal practices differed by randomization group in a phase III trial of the diaphragm with lubricant gel (MIRA) in Sub-Saharan Africa (n = 4925), and if they were associated with consistent use of study methods. At baseline, vaginal practices were commonly reported: vaginal washing (82.77%), wiping (56.47%) and insertion of dry or absorbent materials (20.58%). All three practices decreased during the trial. However, women in the intervention group were significantly more likely to report washing or wiping during follow-up compared to those in the control group. Additionally, washing, wiping, and insertion, were all independently and inversely associated with consistent diaphragm and gel use and with condom use as well, regardless of study arm. A better understanding of the socio-cultural context in which these practices are embedded could improve educational strategies to address these potentially modifiable behaviors, and may benefit future HIV prevention interventions of vaginal methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.