Evidence map›Paper›PMID 20352317›Full record

ArticleAIDS and behavior2010

Physiological and psychosocial factors that predict HIV-related fatigue.

Julie Barroso, Bradley G Hammill, Jane Leserman, Naima Salahuddin, James L Harmon, Brian Wells Pence

Abstract read
In one paragraph

Article in AIDS and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
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  4. The relationship between sexual trauma, peritraumatic dissociation, posttraumatic stress disorder, and HIV-related health in HIV-positive men.Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD) · 2014
    Trial
  5. Effect of armodafinil on cognition in patients with HIV/AIDS and fatigue.Journal of clinical and experimental neuropsychology · 2013
    Trial
  6. Trial
  7. Observational
  8. Article
  9. Article
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  15. Review
  16. Article
  17. Fatigue Symptom Management in People Living With Human Immunodeficiency Virus.Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · 2017
    Article
  18. Article
  19. Fatigue in HIV-Infected People: A Three-Year Observational Study.Journal of pain and symptom management · 2015
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Julie BarrosoSchool of Nursing, Duke University, DUMC 3322, Durham, NC 27710, USA. julie.barroso@duke.edu
Bradley G Hammill
Jane Leserman
Naima Salahuddin
James L Harmon
Brian Wells Pence
Duke University · USClinical Research Institute · USDuke Institute for Health Innovation · USDuke Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Pilot Project for the DTMI CRA ProgramUL1RR024128 · NCRR · DUKE UNIVERSITY · PI CALIFF, ROBERT M · 2006 to 2010
$48.1M
IMPLEMENTATION RESEARCH INSTITUTE FOR MENTAL HEALTH SERVICES IRI-MHSR25MH080916 · NIMH · WASHINGTON UNIVERSITY · PI Byron James Powell · 2009 to 2026
$3.7M
Fatigue in HIV-Positive PeopleR01NR008681 · NINR · DUKE UNIVERSITY · PI BARROSO, JULIE V · 2004 to 2008
$2.5M
NCRR NIH HHS 1UL1RR024128-01NCRR NIH HHS UL1 RR024128NIMH NIH HHS R25 MH080916NINR NIH HHS 5R01NR008681NINR NIH HHS R01 NR008681
6 · The paper itself

Abstract

Fatigue is one of the most common and debilitating symptoms experienced by HIV-infected people. We report the results of our longitudinal analysis of physiological and psychosocial factors that were thought to predict changes in HIV-related fatigue in 128 participants over a 1-year period, in an effort to sort out the complex interplay among a comprehensive set of physiological and psychosocial variables. Physiological measures included hepatic function (aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase, alkaline phosphatase, total bilirubin, hepatitis C status), thyroid function (thyroid stimulating hormone, thyroxine), HIV viral load, immunologic function (CD4, CD8, CD4/CD8 ratio, CD16, CD8CD38), gonadal function (testosterone, dehydroepiandrosterone), hematologic function (hemoglobin, hematocrit, serum erythropoietin), and cellular injury (lactic acid). Psychosocial measures included childhood and adult trauma, anxiety, depression, social support, stressful life events, and post-traumatic stress disorder (PTSD). Unemployment, not being on antiretroviral therapy, having fewer years since HIV diagnosis, more childhood trauma, more stressful life events, less social support, and more psychological distress (e.g., PTSD, anxiety and depression) put HIV-infected persons at risk for greater fatigue intensity and fatigue-related impairment in functioning during 1-year follow-up. Physiological variables did not predict greater fatigue. Stressful life events had both direct and indirect effects on fatigue.

Indexed as

Life Change EventsAdultAgedFatigueFemaleFollow-Up StudiesHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPsychiatric Status Rating ScalesSeverity of Illness IndexSocial SupportStress Disorders, Post-TraumaticStress, Psychological

Identifiers

PMID20352317
PMCPMC2975810
OpenAlexW2064048374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.