ArticleJournal of genetic counseling2010
Considerations for the impact of personal genome information: a study of genomic profiling among genetics and genomics professionals.
Article in Journal of genetic counseling, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Genetic Counseling and Genome Sequencing in Pediatric Rare Disease.Cold Spring Harbor perspectives in medicine · 2020Review
- Article
- The Human Genome Project, and recent advances in personalized genomics.Risk management and healthcare policy · 2015Review
- Understanding patient and provider perceptions and expectations of genomic medicine.Journal of surgical oncology · 2015Review
- Managing Expectational Language: Translational genetic professionals consider the clinical potential of next-generation sequencing technologies.New genetics and society · 2014Article
- Primary care patients' views and decisions about, experience of and reactions to direct-to-consumer genetic testing: a longitudinal study.Journal of community genetics · 2013Article
- Translational Genomic Research: Protocol Development and Initial Outcomes following SNP Testing for Colon Cancer Risk.Translational behavioral medicine · 2013Article
- Perceptions of genetic research in three rural Appalachian Ohio communities.Journal of community genetics · 2013Article
- Genetic counseling as a tool for type 2 diabetes prevention: a genetic counseling framework for common polygenetic disorders.Journal of genetic counseling · 2012Article
- Patients' understanding of and responses to multiplex genetic susceptibility test results.Genetics in medicine : official journal of the American College of Medical Genetics · 2012Article
- Communication about DTC testing: commentary on a 'family experience of personal genomics'.Journal of genetic counseling · 2012Article
- "It's not like judgment day": public understanding of and reactions to personalized genomic risk information.Journal of genetic counseling · 2012Article
- Motivations and perceptions of early adopters of personalized genomics: perspectives from research participants.Public health genomics · 2012Article
- Genomic information as a behavioral health intervention: can it work?Personalized medicine · 2011Article
- Direct-to-consumer personalized genomic testing.Human molecular genetics · 2011Review
- Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling.Journal of general internal medicine · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the expansion of genomic-based clinical applications, it is important to consider the potential impact of this information particularly in terms of how it may be interpreted and applied to personal perceptions of health. As an initial step to exploring this question, we conducted a study to gain insight into potential psychosocial and health motivations for, as well as impact associated with, undergoing testing and disclosure of individual "variomes" (catalogue of genetic variations). To enable the collection of fully informed opinions, 14 participants with advanced training in genetics underwent whole-genome profiling and received individual reports of estimated genomic ancestry, genotype data and reported disease associations. Emotional, cognitive and health behavioral impact was assessed through one-on-one interviews and questionnaires administered pre-testing and 1-week and 3-months post-testing. Notwithstanding the educational and professional bias of our study population, the results identify several areas of research for consideration within additional populations. With the development of new and less costly approaches to genome risk profiling, now available for purchase direct-to-consumers, it is essential that genome science research be conducted in parallel with studies assessing the societal and policy implications of genome information for personal use.
Indexed as
Identifiers
20352309What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.