Evidence map›Paper›PMID 20351400›Full record

ReviewAging2010

Impact papers on aging in 2009.

Mikhail V Blagosklonny, Judy Campisi, David A Sinclair, Andrzej Bartke, Maria A Blasco, William M Bonner, Vilhelm A Bohr, Robert M Brosh, Anne Brunet, Ronald A Depinho and 25 more

Open access · hybridAbstract readReview
In one paragraph

Review in Aging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Aging, longevity and health.Mechanisms of ageing and development · 2011
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 20 institutions in 8 countries.

Mikhail V BlagosklonnyRoswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. Blagosklonny@oncotarget.com
Judy Campisi
David A Sinclair
Andrzej Bartke
Maria A Blasco
William M Bonner
Vilhelm A Bohr
Robert M Brosh
Anne Brunet
Ronald A Depinho
Lawrence A Donehower
Caleb E Finch
Toren Finkel
Myriam Gorospe
Andrei V Gudkov
Michael N Hall
Siegfried Hekimi
Stephen L Helfand
Jan Karlseder
Cynthia Kenyon
Guido Kroemer
Valter Longo
Andre Nussenzweig
Heinz D Osiewacz
Daniel S Peeper
Thomas A Rando
K Lenhard Rudolph
Paolo Sassone-Corsi
Manuel Serrano
Norman E Sharpless
Vladimir P Skulachev
Jonathan L Tilly
John Tower
Eric Verdin
Jan Vijg
National Institute on Aging · USUniversity of Southern California · USInstituto de Salud Carlos III · ESNational Cancer Institute · USRoswell Park Comprehensive Cancer Center · USStanford University · USUniversity of California, San Francisco · USAlbert Einstein College of Medicine · USBaylor College of Medicine · USBrown University · USBuck Institute for Research on Aging · USDana-Farber Cancer Institute · USGoethe University Frankfurt · DEHarvard University · USHarvard University Press · USInserm · FRLomonosov Moscow State University · RUMcGill University · CAMedizinische Hochschule Hannover · DENational Heart Lung and Blood Institute · US

Funding

Relationship between DNA damage detection and signalingZIABC010959 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI NUSSENZWEIG, ANDRE A. · 2009 to 2025
$27.0M
DNA RepairZIABC010283 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI NUSSENZWEIG, ANDRE A. · 2009 to 2025
$27.0M
Influence of Post-transcriptional Gene Regulation on Cell Senescence and AgingZIAAG000393 · NIA · NATIONAL INSTITUTE ON AGING · PI GOROSPE, MYRIAM · 2009 to 2025
$24.1M
Function of RecQ helicases in genome stabilityZIAAG000726 · NIA · NATIONAL INSTITUTE ON AGING · PI BROSH, ROBERT · 2009 to 2025
$13.1M
The role of autophagy in aging and metabolismZIAHL005012 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI FINKEL, TOREN · 2009 to 2017
$11.8M
TELOMERASE IN DEVELOPMENT, SENESCENCE AND NEOPLASIAR01CA084628 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DEPINHO, RONALD ANTHONY · 2000 to 2019
$10.5M
DNA repair dysfunction in neurodegeneration and Alzheimer's DiseaseZIAAG000723 · NIA · NATIONAL INSTITUTE ON AGING · PI BROSH, ROBERT · 2009 to 2025
$9.5M
Oxidative DNA Damage And Its ProcessingZIAAG000727 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2009 to 2022
$8.4M
Studies of Histone Functions in Chromatin; H2AX and DNA DSBsZIABC006140 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BONNER, WILLIAM · 2009 to 2015
$7.8M
Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic StabilityZIAAG000741 · NIA · NATIONAL INSTITUTE ON AGING · PI BROSH, ROBERT · 2009 to 2025
$7.6M
Control of Gene Expression and Life SpanR01AG024353 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HELFAND, STEPHEN L · 2004 to 2018
$5.5M
Model Genetic Systems to Study DNA RepairZIAAG000752 · NIA · NATIONAL INSTITUTE ON AGING · PI BROSH, ROBERT · 2009 to 2025
$4.8M
NCI NIH HHS R01 CA084628NIA NIH HHS R01 AG011833NIA NIH HHS R01 AG028730NIA NIH HHS RF1 AG024353
6 · The paper itself

Abstract

The Editorial Board of Aging reviews research papers published in 2009, which they believe have or will have significant impact on aging research. Among many others, the topics include genes that accelerate aging or in contrast promote longevity in model organisms, DNA damage responses and telomeres, molecular mechanisms of life span extension by calorie restriction and pharmacological interventions into aging. The emerging message in 2009 is that aging is not random but determined by a genetically-regulated longevity network and can be decelerated both genetically and pharmacologically.

Indexed as

Adult Stem CellsAgingAnimalsAutophagyCaloric RestrictionCellular ReprogrammingCircadian RhythmDNA DamageHumansMitochondriaNeoplasmsOxidative StressRNA Processing, Post-TranscriptionalTelomere

Identifiers

PMID20351400
PMCPMC2871240
OpenAlexW2138103041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.