Trial reportJournal of dental research2010
Evidence of intact histatins in the in vivo acquired enamel pellicle.
Trial report in Journal of dental research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 82 citations in OpenAlex.
- The consumption of milk supplemented with probiotics decreases the occurrence of caries and the salivary concentration of hβD-3 in children.Clinical oral investigations · 2021Trial
- Quantitative proteomic analysis of the effect of fluoride on the acquired enamel pellicle.PloS one · 2012Trial
- Exploring the Healing Powers of Histatins: From Oral Health to Therapeutics.International journal of molecular sciences · 2025Review
- Reducing Functional Domain of Histatin 5 Improves Antifungal Activity and Prevents Proteolytic Degradation.Microorganisms · 2025Article
- Influence of Slurry Diluents on Toothpaste Efficacy Against Erosive Tooth Wear: In Vitro and In Situ Studies.Brazilian dental journal · 2025Article
- Acquired pellicle engineering: a fascinating approach to prevent demineralization.Journal of applied oral science : revista FOB · 2025Review
- Energy-dispersive Laue diffraction analysis of the influence of statherin and histatin on the crystallographic texture during human dental enamel demineralization.Journal of applied crystallography · 2024Article
- Erosion behaviour of human, bovine and equine dental hard tissues.Scientific reports · 2023Article
- Mechanistic Insights into Bioengineered Antibiofilm Enamel Pellicles.Journal of dental research · 2023Article
- Protease-inhibitors added to saliva in vitro influence the erosion protective effect of enamel pellicles.Scientific reports · 2023Article
- The composition of the dental pellicle: an updated literature review.Frontiers in oral health · 2023Review
- Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition.Frontiers in cellular and infection microbiology · 2023Article
- Engineered Salivary Peptides Reduce Enamel Demineralization Provoked by CariogenicMicroorganisms · 2022Article
- Modulation ofMicroorganisms · 2022Article
- Bio-inspired special wettability in oral antibacterial applications.Frontiers in bioengineering and biotechnology · 2022Review
- Bioinspired caries preventive strategy via customizable pellicles of saliva-derived protein/peptide constructs.Scientific reports · 2021Article
- pH-Sensitive Chitosan Nanoparticles for Salivary Protein Delivery.Nanomaterials (Basel, Switzerland) · 2021Article
- The salivary pellicle on dental biomaterials.Colloids and surfaces. B, Biointerfaces · 2021Review
- Proteome difference among the salivary proteins adsorbed onto metallic orthodontic brackets and hydroxyapatite discs.PloS one · 2021Article
- Salivary proteomic profile of dogs with and without dental calculus.BMC veterinary research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
Understanding the composition and function of the acquired enamel pellicle (AEP) has been a major goal in oral biology. The aim of this study was to test the hypothesis that intact histatins are part of the in vivo AEP and that histatins after adsorption to HA have effects on in vitro enamel demineralization. This is the first study demonstrating the presence of intact histatins in vivo in the AEP. The in vitro experiments show that all naturally occurring histatins in the AEP have the potential to provide some level of protection against acid injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.