Evidence map›Paper›PMID 20351340›Full record

ArticleHypertension (Dallas, Tex. : 1979)2010

Ultrasound assessment of flow-mediated dilation.

Ryan A Harris, Steven K Nishiyama, D Walter Wray, Russell S Richardson

3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 331 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
331citing papers in PubMed, 2 pooled it
20.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02549534 completednot on this mapstarted 2015, after this paper: background citation

Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer

TypeobservationalSponsorIndiana UniversityRan2015 to 2016Enrolled29ConditionsPeripheral NeuropathyArmsAxon Reflexes, Axon Flares, Self-Reported Signs & Symptoms of CIPN
NCT03272737 nacompletednot on this mapstarted 2018, after this paper: background citation

Effect of Low Intensity Strength Training Combined With Moderate Blood Flow Restriction on Muscle Vasodilatation and Arterial Stiffness in Elders With Low Gait Velocity.

TypeinterventionalSponsorHospital Israelita Albert EinsteinRan2018 to 2022Enrolled26ConditionsFrail Elderly SyndromeArms1RM Test, Speed gait test, Venous occlusion plethysmography protocol, Measurement of Arterial Stiffness - Pulse Wave Analysis and Velocity, Isometric handgrip exercise protocol
NCT05423470 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals

TypeinterventionalSponsorUniversity of Texas at AustinRan2019 to 2022Enrolled41ConditionsIntermittent HypoxiaArmsIntermittent hypoxia, Intermittent normoxia
3 · Its place in the literature

Who cites it

331 citing papers in PubMed, 2 syntheses or guidelines pooled it, 646 citations in OpenAlex.

  1. Pooled it
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  3. Beneficial vascular effects of oral phosphatidylserine supplementation in type 2 diabetes.Journal of applied physiology (Bethesda, Md. : 1985) · 2026
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  16. No effect of acute tetrahydrobiopterin (BHJournal of applied physiology (Bethesda, Md. : 1985) · 2022
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  19. The Effect of Magnesium Supplementation on Endothelial Function: A Randomised Cross-Over Pilot Study.International journal of environmental research and public health · 2021
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271 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ryan A HarrisGeorgia Prevention Institute, Medical College of Georgia, Augusta, GA 30912, USA. ryharris@mcg.edu
Steven K Nishiyama
D Walter Wray
Russell S Richardson
Prevention Institute · US

Funding

VENTILATION BLOOD FLOW IN HEALTH AND DISEASEP01HL017731 · NHLBI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI WAGNER, PETER D · 1985 to 2004
$10.6M
NHLBI NIH HHS P01 HL017731NHLBI NIH HHS P01-HL-0918830PHS HHS 15RT-0100
6 · The paper itself

Abstract

Developed in 1992, the flow-mediated dilation test is now the most commonly used noninvasive assessment of vascular endothelial function in humans. Since its inception, scientists have refined their understanding of the physiology, analysis, and interpretation of this measurement. Recently, a significant growth of knowledge has added to our understanding and implementation of this clinically relevant research methodology. Therefore, this tutorial provides timely insight into recent advances and practical information related to the ultrasonic assessment of vascular endothelial function in humans.

Indexed as

Arterial Occlusive DiseasesBlood Flow VelocityCaffeineCardiovascular DiseasesEndothelium, VascularFemaleHumansHyperemiaHypertensionMenstrual CycleRisk FactorsSmokingSoftwareUltrasonographyUltrasonography, Doppler, DuplexVasodilationCaffeine

Identifiers

PMID20351340
PMCPMC2878744
OpenAlexW2136329682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.